Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   ST4078_RS00395 Genome accession   NZ_CP065477
Coordinates   67740..68330 (+) Length   196 a.a.
NCBI ID   WP_011680603.1    Uniprot ID   Q03MX8
Organism   Streptococcus thermophilus strain 4078     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 62740..73330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4078_RS09710 (ST4078_00360) - 63870..64325 (-) 456 Protein_51 DUF3021 domain-containing protein -
  ST4078_RS00375 (ST4078_00365) - 64322..64713 (-) 392 Protein_52 LytTR family DNA-binding domain-containing protein -
  ST4078_RS00380 (ST4078_00370) - 64937..65242 (+) 306 WP_002949050.1 hypothetical protein -
  ST4078_RS00385 (ST4078_00375) hexB 65294..67237 (+) 1944 WP_014607839.1 DNA mismatch repair endonuclease MutL Machinery gene
  ST4078_RS00390 (ST4078_00380) - 67367..67588 (+) 222 WP_002949052.1 hypothetical protein -
  ST4078_RS00395 (ST4078_00385) ruvA 67740..68330 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA Machinery gene
  ST4078_RS00400 (ST4078_00390) - 68337..68891 (+) 555 WP_011680604.1 DNA-3-methyladenine glycosylase I -
  ST4078_RS00405 (ST4078_00395) cinA 68987..70258 (+) 1272 WP_011680605.1 competence/damage-inducible protein A Machinery gene
  ST4078_RS00410 (ST4078_00400) recA 70294..71448 (+) 1155 WP_002949056.1 recombinase RecA Machinery gene
  ST4078_RS00415 (ST4078_00405) spx 71625..72023 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21683.98 Da        Isoelectric Point: 5.2834

>NTDB_id=447336 ST4078_RS00395 WP_011680603.1 67740..68330(+) (ruvA) [Streptococcus thermophilus strain 4078]
MYDYIKGTLVKITAKHIVIETNGLGYIVTVANPYSFSDQMNQTIQVYLHQVIRDDAHLLFGFHTEDEKEVFLKLISVSGI
GPTTALAIVAVDDNQGLVAAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFAELPAETTNTTANQTAGNQQLDEAMEALL
ALGYKATELKKVKAFFEDTNETAEQYIKSALKMLMK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=447336 ST4078_RS00395 WP_011680603.1 67740..68330(+) (ruvA) [Streptococcus thermophilus strain 4078]
ATGTATGATTATATCAAGGGCACCCTAGTAAAAATCACAGCCAAACACATTGTCATAGAAACAAATGGTCTAGGATATAT
TGTCACTGTGGCTAATCCCTACAGCTTTTCTGATCAAATGAATCAGACTATCCAAGTGTATCTTCATCAAGTTATTAGAG
ATGATGCCCACCTACTTTTTGGTTTTCATACTGAAGATGAGAAAGAAGTTTTTCTTAAGTTGATTTCTGTTTCTGGGATA
GGTCCGACGACTGCTCTAGCCATAGTGGCTGTGGATGATAATCAGGGACTTGTTGCTGCTATTGATAATAGTGACATCAA
ATACCTGATGAAATTTCCAAAGATTGGTAAAAAGACTGCTCAACAAATGGTTCTTGATCTGGCAGGAAAATTTGCAGAGT
TACCAGCAGAAACGACCAATACTACGGCAAATCAGACTGCAGGAAATCAACAGTTGGATGAAGCTATGGAAGCTTTGCTT
GCTCTTGGGTACAAAGCCACAGAGCTTAAGAAAGTGAAAGCCTTCTTTGAGGATACCAATGAAACGGCAGAGCAATATAT
TAAGTCCGCTCTTAAAATGTTGATGAAGTGA

Domains

Predicted by InterProScan.

RuvA, C-terminal domain (RuvA_C)

(151-195)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q03MX8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.5

100

0.679
  ruvA Streptococcus pneumoniae R6

66.5

100

0.679
  ruvA Streptococcus pneumoniae D39

66.5

100

0.679
  ruvA Bacillus subtilis subsp. subtilis str. 168

42.647

100

0.444