Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   ST4052_RS06510 Genome accession   NZ_CP065476
Coordinates   1254622..1255707 (-) Length   361 a.a.
NCBI ID   WP_011226304.1    Uniprot ID   Q5M3H6
Organism   Streptococcus thermophilus strain 4052     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1249622..1260707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4052_RS06480 (ST4052_06555) - 1249988..1250803 (-) 816 WP_011227405.1 Cof-type HAD-IIB family hydrolase -
  ST4052_RS06485 (ST4052_06560) - 1250796..1251590 (-) 795 WP_059257398.1 HAD family hydrolase -
  ST4052_RS06490 (ST4052_06565) - 1251773..1252150 (+) 378 WP_011226300.1 GntR family transcriptional regulator -
  ST4052_RS06495 (ST4052_06570) - 1252155..1252853 (+) 699 WP_011226301.1 ABC transporter ATP-binding protein -
  ST4052_RS06500 (ST4052_06575) - 1252865..1253650 (+) 786 WP_002951425.1 hypothetical protein -
  ST4052_RS06505 (ST4052_06580) - 1253700..1254629 (-) 930 WP_002951426.1 ATP-binding cassette domain-containing protein -
  ST4052_RS06510 (ST4052_06585) amiE 1254622..1255707 (-) 1086 WP_011226304.1 ABC transporter ATP-binding protein Regulator
  ST4052_RS06515 (ST4052_06590) amiD 1255717..1256643 (-) 927 WP_002946409.1 oligopeptide ABC transporter permease OppC Regulator
  ST4052_RS06520 (ST4052_06595) amiC 1256643..1258136 (-) 1494 WP_011227407.1 ABC transporter permease Regulator
  ST4052_RS06525 (ST4052_06600) amiA 1258198..1260165 (-) 1968 WP_347100844.1 peptide ABC transporter substrate-binding protein Regulator
  ST4052_RS06530 (ST4052_06605) - 1260369..1260559 (-) 191 Protein_1231 IS3 family transposase -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 39864.62 Da        Isoelectric Point: 4.7435

>NTDB_id=447291 ST4052_RS06510 WP_011226304.1 1254622..1255707(-) (amiE) [Streptococcus thermophilus strain 4052]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=447291 ST4052_RS06510 WP_011226304.1 1254622..1255707(-) (amiE) [Streptococcus thermophilus strain 4052]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-300)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M3H6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus thermophilus LMG 18311

100

100

1
  amiE Streptococcus thermophilus LMD-9

100

100

1
  amiE Streptococcus salivarius strain HSISS4

96.953

100

0.97
  oppD Streptococcus mutans UA159

54.441

96.676

0.526