Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   GE021_RS05000 Genome accession   NZ_CP053792
Coordinates   988093..989403 (+) Length   436 a.a.
NCBI ID   WP_125074024.1    Uniprot ID   A0A3P5Y1D6
Organism   Streptococcus canis strain HL_77_1     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 983093..994403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS04990 (GE021_004990) - 985608..987134 (-) 1527 WP_125075051.1 IS1182 family transposase -
  GE021_RS04995 (GE021_004995) ciaR 987426..988100 (+) 675 WP_003048303.1 response regulator transcription factor Regulator
  GE021_RS05000 (GE021_005000) ciaH 988093..989403 (+) 1311 WP_125074024.1 cell wall metabolism sensor histidine kinase WalK Regulator
  GE021_RS05005 (GE021_005005) rpsT 989848..990096 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  GE021_RS05010 (GE021_005010) coaA 990150..991070 (-) 921 WP_125074023.1 type I pantothenate kinase -
  GE021_RS05015 (GE021_005015) - 991339..991938 (+) 600 WP_125074022.1 class I SAM-dependent methyltransferase -
  GE021_RS05020 (GE021_005020) - 991925..993202 (+) 1278 WP_125074021.1 pyrimidine-nucleoside phosphorylase -
  GE021_RS05025 (GE021_005025) deoC 993218..993880 (+) 663 WP_164407555.1 deoxyribose-phosphate aldolase -
  GE021_RS05030 (GE021_005030) - 993867..994256 (+) 390 WP_125074019.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49749.26 Da        Isoelectric Point: 9.1190

>NTDB_id=447278 GE021_RS05000 WP_125074024.1 988093..989403(+) (ciaH) [Streptococcus canis strain HL_77_1]
MSKLKKEILSDQYTHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNII
KALPDSDSSKLLGSPAANTDIILFSANGTILNSFNAFSNYQNFHLDERRLGTIVTTSLVNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVDQLDSANERYEQIIIIVMVIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDAQFFDTIFKNYQLVVEESGKVFRSDN
QVNRILKMDEALLKQLMTILVDNAIKYTDKNGVVEIKVKTTDKTLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVTSLKGSITVKDNFPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=447278 GE021_RS05000 WP_125074024.1 988093..989403(+) (ciaH) [Streptococcus canis strain HL_77_1]
ATGAGTAAATTAAAAAAAGAGATTCTGTCAGATCAGTACACTCACTTTTTCCATTTTTTTGCGGTCTTTACAGGTATTTT
TGTCATTATGACCATTATTATTTTACAGATTATGAGGTTTGGGGTTTATTCGTCTGTTGATAGTAGCCTGATTTCTGTTA
GTAATAATGCTAGTAGCTATGCCAATCGAACCATGGCTAGAATATCCTCCTTTTATTTTGATGCTGAAAATAATATTATT
AAGGCGCTACCTGACTCTGATAGTTCAAAATTACTAGGTTCCCCTGCAGCTAATACAGATATTATTTTGTTCAGTGCTAA
TGGGACGATTTTAAATTCCTTCAATGCCTTCTCCAATTACCAAAATTTTCATCTGGACGAACGACGGTTAGGAACCATCG
TGACAACTAGTCTCGTGAATTTTTATGGTCAAGAAGAAAAGTACCATACGATAACTGTTAGGGTTCATATCAAAAATTAC
CCTGCTGTCGCTTATATGATGGCTGTTGTCAATGTGGATCAATTGGATAGCGCTAATGAACGCTATGAGCAAATCATCAT
CATTGTGATGGTTATCTTTTGGCTGATTTCCATTTTAGCTAGTATTTATTTATCTAAGTGGAGTCGAAAACCGATTTTGG
AAAGTTATGAAAAGCAAAAGATGTTTGTGGAAAATGCCAGCCATGAATTAAGAACCCCTCTAGCTGTTTTACAAAACCGC
TTGGAATCCCTTTTTCGAAAACCTAACGAAACCATTTTGGAAAATAGTGAGCACCTTGCCTCTAGTTTGGACGAAGTCCG
AAACATGCGTATTCTAACGACCAATCTATTGAATTTGGCCAGGCGAGATGACGGTATCAATCCGCAATGGACAGATTTGG
ATGCTCAATTCTTTGATACCATTTTTAAGAACTATCAATTAGTTGTTGAAGAATCTGGCAAAGTCTTTCGCTCCGATAAT
CAAGTCAATCGCATCTTGAAGATGGACGAGGCATTATTAAAACAACTCATGACGATTTTAGTCGATAATGCCATCAAATA
CACCGATAAAAATGGAGTAGTTGAGATAAAGGTCAAAACAACCGATAAAACCTTGCTCATTTCGGTTATTGATAATGGGC
CAGGGATAAAAGACGAAGAGAAGAAAAAGATTTTTGACCGATTTTATCGGGTTGATAAAGCTAGAACACGCCAGACAGGT
GGCTTTGGCTTAGGATTAGCATTAGCCCAACAGATTGTGACGTCATTAAAAGGAAGTATCACAGTAAAAGATAACTTCCC
TAAAGGTAGTATTTTTGAAGTCAAATTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P5Y1D6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.666

100

0.578
  ciaH Streptococcus pneumoniae Rx1

50.913

100

0.511
  ciaH Streptococcus pneumoniae D39

50.913

100

0.511
  ciaH Streptococcus pneumoniae R6

50.913

100

0.511
  ciaH Streptococcus pneumoniae TIGR4

50.913

100

0.511