Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | GE021_RS04300 | Genome accession | NZ_CP053792 |
| Coordinates | 869104..870333 (+) | Length | 409 a.a. |
| NCBI ID | WP_125073848.1 | Uniprot ID | A0A3P5Y7D1 |
| Organism | Streptococcus canis strain HL_77_1 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 862714..915603 | 869104..870333 | within | 0 |
Gene organization within MGE regions
Location: 862714..915603
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GE021_RS04265 (GE021_004265) | fni | 862714..863706 (+) | 993 | WP_125073854.1 | type 2 isopentenyl-diphosphate Delta-isomerase | - |
| GE021_RS11530 (GE021_004270) | - | 864015..864161 (+) | 147 | WP_367302866.1 | transposase | - |
| GE021_RS11535 (GE021_004275) | - | 864349..864603 (+) | 255 | WP_125073853.1 | IS3 family transposase | - |
| GE021_RS04280 (GE021_004280) | - | 864701..865975 (-) | 1275 | WP_125073852.1 | hydroxymethylglutaryl-CoA reductase, degradative | - |
| GE021_RS04285 (GE021_004285) | - | 865956..867137 (-) | 1182 | WP_125073851.1 | hydroxymethylglutaryl-CoA synthase | - |
| GE021_RS04290 (GE021_004290) | - | 867345..868184 (+) | 840 | WP_125073850.1 | thymidylate synthase | - |
| GE021_RS04295 (GE021_004295) | - | 868264..868761 (+) | 498 | WP_125073849.1 | dihydrofolate reductase | - |
| GE021_RS04300 (GE021_004300) | clpX | 869104..870333 (+) | 1230 | WP_125073848.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| GE021_RS04305 (GE021_004305) | yihA | 870343..870942 (+) | 600 | WP_125073847.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| GE021_RS04310 (GE021_004310) | - | 871092..871832 (+) | 741 | WP_125073846.1 | hypothetical protein | - |
| GE021_RS04315 (GE021_004315) | - | 871961..872927 (-) | 967 | Protein_819 | IS30 family transposase | - |
| GE021_RS04320 (GE021_004320) | - | 873073..873870 (-) | 798 | Protein_820 | IS982 family transposase | - |
| GE021_RS04325 (GE021_004325) | - | 873966..874346 (-) | 381 | WP_125073844.1 | hypothetical protein | - |
| GE021_RS04330 (GE021_004330) | - | 874399..874557 (-) | 159 | WP_142998413.1 | helix-turn-helix domain-containing protein | - |
| GE021_RS04335 (GE021_004335) | - | 875410..876606 (-) | 1197 | WP_164407705.1 | site-specific integrase | - |
| GE021_RS04340 (GE021_004340) | - | 876959..878161 (-) | 1203 | WP_302051309.1 | IS110 family transposase | - |
| GE021_RS04345 (GE021_004345) | - | 878410..879003 (-) | 594 | WP_164407456.1 | HIRAN domain-containing protein | - |
| GE021_RS04350 (GE021_004350) | - | 879015..879398 (-) | 384 | WP_164407458.1 | ImmA/IrrE family metallo-endopeptidase | - |
| GE021_RS04355 (GE021_004355) | - | 879402..879752 (-) | 351 | WP_063629762.1 | helix-turn-helix domain-containing protein | - |
| GE021_RS04360 (GE021_004360) | - | 880042..880206 (+) | 165 | WP_164407460.1 | hypothetical protein | - |
| GE021_RS04365 (GE021_004365) | - | 880248..880451 (+) | 204 | WP_015984784.1 | hypothetical protein | - |
| GE021_RS11430 | - | 880453..880584 (+) | 132 | WP_261006046.1 | hypothetical protein | - |
| GE021_RS04370 (GE021_004370) | - | 880696..881025 (-) | 330 | WP_164407462.1 | hypothetical protein | - |
| GE021_RS04375 (GE021_004375) | - | 881025..881456 (-) | 432 | WP_164407464.1 | hypothetical protein | - |
| GE021_RS04380 (GE021_004380) | - | 881516..882235 (+) | 720 | WP_164407466.1 | ORF6C domain-containing protein | - |
| GE021_RS04385 (GE021_004385) | - | 882309..882566 (+) | 258 | WP_164407468.1 | DNA-binding protein | - |
| GE021_RS04390 (GE021_004390) | - | 882704..882892 (+) | 189 | WP_164407470.1 | hypothetical protein | - |
| GE021_RS04395 (GE021_004395) | - | 882905..883489 (+) | 585 | WP_164407472.1 | hypothetical protein | - |
| GE021_RS04400 (GE021_004400) | - | 883538..884449 (+) | 912 | WP_217267494.1 | DnaD domain protein | - |
| GE021_RS04405 (GE021_004405) | - | 884485..884712 (+) | 228 | WP_164407476.1 | hypothetical protein | - |
| GE021_RS04410 (GE021_004410) | - | 884726..884932 (+) | 207 | WP_155782846.1 | hypothetical protein | - |
| GE021_RS04415 (GE021_004415) | - | 884942..885127 (+) | 186 | WP_085577387.1 | hypothetical protein | - |
| GE021_RS04420 (GE021_004420) | - | 885124..885288 (+) | 165 | WP_164407478.1 | hypothetical protein | - |
| GE021_RS04425 (GE021_004425) | - | 885285..885569 (+) | 285 | WP_164407480.1 | hypothetical protein | - |
| GE021_RS04430 (GE021_004430) | - | 885573..886055 (+) | 483 | WP_164407482.1 | class I SAM-dependent methyltransferase | - |
| GE021_RS04435 (GE021_004435) | - | 886057..886791 (+) | 735 | WP_164407484.1 | DNA cytosine methyltransferase | - |
| GE021_RS04440 (GE021_004440) | - | 886772..887275 (+) | 504 | WP_254388134.1 | DNA cytosine methyltransferase | - |
| GE021_RS11125 | - | 887265..887831 (+) | 567 | WP_164407486.1 | DUF3310 domain-containing protein | - |
| GE021_RS04450 (GE021_004450) | - | 887824..888156 (+) | 333 | WP_002986215.1 | hypothetical protein | - |
| GE021_RS04455 (GE021_004455) | - | 888149..888376 (+) | 228 | WP_164407488.1 | hypothetical protein | - |
| GE021_RS04460 (GE021_004460) | ssb | 888366..888758 (+) | 393 | WP_155782953.1 | single-stranded DNA-binding protein | Machinery gene |
| GE021_RS04465 (GE021_004465) | - | 888772..889050 (+) | 279 | WP_029713970.1 | hypothetical protein | - |
| GE021_RS04470 (GE021_004470) | - | 889047..889388 (+) | 342 | WP_164407490.1 | helix-turn-helix domain-containing protein | - |
| GE021_RS04475 (GE021_004475) | - | 889511..890338 (+) | 828 | WP_164407492.1 | prohibitin family protein | - |
| GE021_RS04480 (GE021_004480) | - | 890353..890754 (+) | 402 | WP_164407495.1 | transcriptional regulator | - |
| GE021_RS04485 (GE021_004485) | - | 890914..891489 (+) | 576 | WP_011054435.1 | site-specific integrase | - |
| GE021_RS04490 (GE021_004490) | - | 891643..891939 (+) | 297 | WP_164407497.1 | hypothetical protein | - |
| GE021_RS04495 (GE021_004495) | - | 891978..892364 (+) | 387 | WP_164407499.1 | hypothetical protein | - |
| GE021_RS04500 (GE021_004500) | - | 892357..892662 (+) | 306 | WP_164407501.1 | HNH endonuclease | - |
| GE021_RS04505 (GE021_004505) | - | 892805..893122 (+) | 318 | WP_164407503.1 | P27 family phage terminase small subunit | - |
| GE021_RS04510 (GE021_004510) | - | 893135..894865 (+) | 1731 | WP_164407506.1 | terminase large subunit | - |
| GE021_RS04515 (GE021_004515) | - | 895233..896420 (+) | 1188 | WP_164407508.1 | phage portal protein | - |
| GE021_RS04520 (GE021_004520) | - | 896401..897207 (+) | 807 | WP_164407510.1 | head maturation protease, ClpP-related | - |
| GE021_RS04525 (GE021_004525) | - | 897224..898357 (+) | 1134 | WP_164407512.1 | phage major capsid protein | - |
| GE021_RS04530 (GE021_004530) | - | 898378..898551 (+) | 174 | WP_164407515.1 | hypothetical protein | - |
| GE021_RS04535 (GE021_004535) | - | 898551..898859 (+) | 309 | WP_027970290.1 | hypothetical protein | - |
| GE021_RS04540 (GE021_004540) | - | 898852..899214 (+) | 363 | WP_037562728.1 | hypothetical protein | - |
| GE021_RS04545 (GE021_004545) | - | 899216..899614 (+) | 399 | WP_143978750.1 | HK97 gp10 family phage protein | - |
| GE021_RS04550 (GE021_004550) | - | 899607..899987 (+) | 381 | WP_164407517.1 | hypothetical protein | - |
| GE021_RS04555 (GE021_004555) | - | 899999..900583 (+) | 585 | WP_164407519.1 | major tail protein | - |
| GE021_RS04560 (GE021_004560) | - | 900679..900981 (+) | 303 | WP_164407521.1 | hypothetical protein | - |
| GE021_RS04565 (GE021_004565) | - | 900996..901163 (+) | 168 | WP_164407454.1 | hypothetical protein | - |
| GE021_RS04570 (GE021_004570) | - | 901207..905307 (+) | 4101 | WP_164407523.1 | phage tail tape measure protein | - |
| GE021_RS04575 (GE021_004575) | - | 905320..906090 (+) | 771 | WP_164407525.1 | distal tail protein Dit | - |
| GE021_RS04580 (GE021_004580) | - | 906087..908135 (+) | 2049 | WP_164407527.1 | phage tail spike protein | - |
| GE021_RS11435 | - | 908135..909319 (+) | 1185 | WP_302051313.1 | hypothetical protein | - |
| GE021_RS04590 (GE021_004590) | - | 909316..909690 (+) | 375 | WP_164407529.1 | hypothetical protein | - |
| GE021_RS04595 (GE021_004595) | - | 909702..911405 (+) | 1704 | WP_172774133.1 | gp58-like family protein | - |
| GE021_RS04600 (GE021_004600) | - | 911417..911845 (+) | 429 | WP_164407648.1 | DUF1617 family protein | - |
| GE021_RS04605 (GE021_004605) | - | 911848..912273 (+) | 426 | WP_143928019.1 | DUF1366 domain-containing protein | - |
| GE021_RS04610 (GE021_004610) | - | 912299..912460 (+) | 162 | WP_164406953.1 | hypothetical protein | - |
| GE021_RS04615 (GE021_004615) | - | 912469..912843 (+) | 375 | WP_125073767.1 | phage holin family protein | - |
| GE021_RS04620 (GE021_004620) | - | 912966..914183 (+) | 1218 | WP_164406948.1 | peptidoglycan amidohydrolase family protein | - |
| GE021_RS04625 (GE021_004625) | - | 914327..914578 (-) | 252 | WP_164406943.1 | hypothetical protein | - |
| GE021_RS04630 (GE021_004630) | - | 914719..914865 (-) | 147 | WP_164406938.1 | hypothetical protein | - |
| GE021_RS04635 (GE021_004635) | - | 915018..915227 (+) | 210 | WP_011054450.1 | helix-turn-helix domain-containing protein | - |
| GE021_RS04640 (GE021_004640) | prx | 915421..915603 (+) | 183 | WP_164406925.1 | Paratox | Regulator |
Sequence
Protein
Download Length: 409 a.a. Molecular weight: 44972.48 Da Isoelectric Point: 4.6207
>NTDB_id=447274 GE021_RS04300 WP_125073848.1 869104..870333(+) (clpX) [Streptococcus canis strain HL_77_1]
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLNILNQYVVGQDR
AKRALAVAVYNHYKRVSFAESRDDEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIASKAIERKTGARGLRSIIEETMLDIMFEVPSQEDVTKVRVTKAAVEG
KSKPVLETA
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLNILNQYVVGQDR
AKRALAVAVYNHYKRVSFAESRDDEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIASKAIERKTGARGLRSIIEETMLDIMFEVPSQEDVTKVRVTKAAVEG
KSKPVLETA
Nucleotide
Download Length: 1230 bp
>NTDB_id=447274 GE021_RS04300 WP_125073848.1 869104..870333(+) (clpX) [Streptococcus canis strain HL_77_1]
ATGGCAGGAAATCGTACTAACGATATTAAGGTATATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTCAAAAAAATCAT
TGCAGGGAACAACGTTTTTATTTGTAATGAATGTGTAGCCCTATCACAGGAAATTATCAAAGAAGAATTGGCAGAAGAAG
TACTGGCTGATTTAACAGAGGTTCCAAAACCAAAAGAACTTCTTAATATTTTAAACCAATACGTGGTTGGTCAAGACCGT
GCCAAGCGGGCCTTAGCAGTTGCAGTCTATAACCATTACAAGCGTGTTTCATTTGCTGAAAGCCGTGATGACGAAGATGT
TGATTTGCAAAAATCAAATATTTTAATGATTGGCCCAACAGGCTCTGGAAAGACGTTTTTGGCACAGACATTGGCTAAGA
GTTTAAATGTGCCTTTTGCTATTGCAGATGCTACCTCCTTAACAGAAGCTGGATATGTGGGAGAGGACGTTGAAAATATC
CTTCTCAAACTGATTCAAGCAGCGGATTATAATGTGGAGCGAGCAGAGCGTGGCATCATCTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGTGAGAATGTGTCCATCACACGAGATGTGTCAGGCGAGGGAGTACAACAGGCTCTGTTAAAAATTA
TTGAAGGTACTGTTGCGAGTGTTCCTCCTCAAGGTGGGCGGAAGCATCCTAATCAGGAAATGATTCAAATTGATACAAAA
AATATCTTATTCATTGTTGGTGGGGCATTTGATGGCATTGAGGAGATTGTCAAACAGCGTCTAGGGGAAAAAATCATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGATAATGCTTCTTACATGCAAGAAATTATATCAGAAGATATCCAAAAATTTG
GTCTTATTCCTGAATTTATTGGCCGTTTACCAGTTGTGGCAGCCCTTGAACAGCTTAACACCTCAGACTTGATCCAAATA
TTAACAGAGCCAAGAAATGCTCTTGTTAAACAATACCAAGCCTTGTTATCTTATGATGGTGTTGAATTAGAATTTGAGAA
GGGTGCCCTTGAAGCCATTGCAAGTAAAGCGATTGAACGCAAAACAGGAGCACGTGGTCTCCGTTCTATCATTGAAGAAA
CCATGTTGGATATTATGTTTGAAGTGCCAAGTCAAGAAGATGTGACTAAAGTTCGTGTTACCAAAGCTGCAGTTGAAGGC
AAGTCAAAACCCGTTTTAGAAACAGCATAA
ATGGCAGGAAATCGTACTAACGATATTAAGGTATATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTCAAAAAAATCAT
TGCAGGGAACAACGTTTTTATTTGTAATGAATGTGTAGCCCTATCACAGGAAATTATCAAAGAAGAATTGGCAGAAGAAG
TACTGGCTGATTTAACAGAGGTTCCAAAACCAAAAGAACTTCTTAATATTTTAAACCAATACGTGGTTGGTCAAGACCGT
GCCAAGCGGGCCTTAGCAGTTGCAGTCTATAACCATTACAAGCGTGTTTCATTTGCTGAAAGCCGTGATGACGAAGATGT
TGATTTGCAAAAATCAAATATTTTAATGATTGGCCCAACAGGCTCTGGAAAGACGTTTTTGGCACAGACATTGGCTAAGA
GTTTAAATGTGCCTTTTGCTATTGCAGATGCTACCTCCTTAACAGAAGCTGGATATGTGGGAGAGGACGTTGAAAATATC
CTTCTCAAACTGATTCAAGCAGCGGATTATAATGTGGAGCGAGCAGAGCGTGGCATCATCTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGTGAGAATGTGTCCATCACACGAGATGTGTCAGGCGAGGGAGTACAACAGGCTCTGTTAAAAATTA
TTGAAGGTACTGTTGCGAGTGTTCCTCCTCAAGGTGGGCGGAAGCATCCTAATCAGGAAATGATTCAAATTGATACAAAA
AATATCTTATTCATTGTTGGTGGGGCATTTGATGGCATTGAGGAGATTGTCAAACAGCGTCTAGGGGAAAAAATCATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGATAATGCTTCTTACATGCAAGAAATTATATCAGAAGATATCCAAAAATTTG
GTCTTATTCCTGAATTTATTGGCCGTTTACCAGTTGTGGCAGCCCTTGAACAGCTTAACACCTCAGACTTGATCCAAATA
TTAACAGAGCCAAGAAATGCTCTTGTTAAACAATACCAAGCCTTGTTATCTTATGATGGTGTTGAATTAGAATTTGAGAA
GGGTGCCCTTGAAGCCATTGCAAGTAAAGCGATTGAACGCAAAACAGGAGCACGTGGTCTCCGTTCTATCATTGAAGAAA
CCATGTTGGATATTATGTTTGAAGTGCCAAGTCAAGAAGATGTGACTAAAGTTCGTGTTACCAAAGCTGCAGTTGAAGGC
AAGTCAAAACCCGTTTTAGAAACAGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
89.242 |
100 |
0.892 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.354 |
98.044 |
0.572 |