Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GE021_RS02255 Genome accession   NZ_CP053792
Coordinates   443359..444045 (+) Length   228 a.a.
NCBI ID   WP_003046762.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 438359..449045
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS02230 (GE021_002230) ktrB 438464..439840 (-) 1377 WP_003046748.1 potassium uptake transporter channel subunit KtrB -
  GE021_RS02235 (GE021_002235) rsmG 439921..440634 (-) 714 WP_125074737.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  GE021_RS02240 (GE021_002240) - 440784..441341 (+) 558 WP_125074736.1 LemA family protein -
  GE021_RS02245 (GE021_002245) htpX 441389..442291 (+) 903 WP_125074855.1 zinc metalloprotease HtpX -
  GE021_RS02250 (GE021_002250) - 442564..443097 (+) 534 WP_164406356.1 DUF177 domain-containing protein -
  GE021_RS02255 (GE021_002255) covR 443359..444045 (+) 687 WP_003046762.1 two-component system response regulator CovR Regulator
  GE021_RS02260 (GE021_002260) - 444051..445553 (+) 1503 WP_125074853.1 HAMP domain-containing histidine kinase -
  GE021_RS02265 (GE021_002265) nrdR 445774..446268 (+) 495 WP_003046767.1 transcriptional regulator NrdR -
  GE021_RS02270 (GE021_002270) - 446252..447421 (+) 1170 WP_125074852.1 DnaD domain protein -
  GE021_RS02275 (GE021_002275) dnaI 447422..448324 (+) 903 WP_125074851.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26575.63 Da        Isoelectric Point: 4.6541

>NTDB_id=447263 GE021_RS02255 WP_003046762.1 443359..444045(+) (covR) [Streptococcus canis strain HL_77_1]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKLPSQGIYRDLVLNPQNRSVNRGDDEIPLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=447263 GE021_RS02255 WP_003046762.1 443359..444045(+) (covR) [Streptococcus canis strain HL_77_1]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTCGCAAGATTTGTTTCACTTGAACTGCAACATGAAGGTTA
TGAAGTAACCGTTGAAGTAAACGGTCGTGAAGGGTTAGAAACTGCCTTGGAAAAGGATTTTGATTTAATCTTGCTTGACT
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACCCGTCGCTTACAGACTGAAAAAACAACATATATCATGATGATGACG
GCACGTGATTCGATTATGGATGTGGTGGCAGGCTTGGACCGTGGTGCGGATGACTACATTGTTAAGCCATTTGCGATTGA
AGAATTGTTGGCGCGTATTCGTGCAATTTTCCGTCGTCAAGATATTGAATCTGAAAAGAAACTGCCTAGTCAAGGGATTT
ATCGTGACTTGGTCTTGAACCCACAAAACCGTTCGGTTAATCGTGGGGATGATGAAATTCCCCTCACTAAACGTGAATAC
GACTTGCTTAGCATTTTGATGACAAACATGAACCGTGTGATGACACGTGAAGAATTGCTCTCAAATGTTTGGAAATATGA
TGAGGCAGTTGAAACAAACGTTGTTGATGTTTACATTCGTTACCTTCGTGGTAAAGTTGACATCCCAGGTAAGGAATCTT
ATATCCAAACCGTTCGCGGCATGGGATATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.103

100

0.439
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.421