Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GE022_RS07645 Genome accession   NZ_CP053790
Coordinates   1564220..1564906 (-) Length   228 a.a.
NCBI ID   WP_003046762.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1559220..1569906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS07625 (GE022_007615) dnaI 1559943..1560845 (-) 903 WP_159305797.1 primosomal protein DnaI -
  GE022_RS07630 (GE022_007620) - 1560846..1562015 (-) 1170 WP_164405568.1 DnaD domain protein -
  GE022_RS07635 (GE022_007625) nrdR 1561999..1562493 (-) 495 WP_003046767.1 transcriptional regulator NrdR -
  GE022_RS07640 (GE022_007630) - 1562712..1564214 (-) 1503 WP_003046765.1 HAMP domain-containing sensor histidine kinase -
  GE022_RS07645 (GE022_007635) covR 1564220..1564906 (-) 687 WP_003046762.1 two-component system response regulator CovR Regulator
  GE022_RS07650 (GE022_007640) - 1565167..1565700 (-) 534 WP_003046759.1 YceD family protein -
  GE022_RS07655 (GE022_007645) htpX 1565973..1566875 (-) 903 WP_099982901.1 zinc metalloprotease HtpX -
  GE022_RS07660 (GE022_007650) - 1566923..1567480 (-) 558 WP_164405569.1 LemA family protein -
  GE022_RS07665 (GE022_007655) rsmG 1567630..1568343 (+) 714 WP_003046751.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  GE022_RS07670 (GE022_007660) ktrB 1568424..1569800 (+) 1377 WP_003046748.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26575.63 Da        Isoelectric Point: 4.6541

>NTDB_id=447225 GE022_RS07645 WP_003046762.1 1564220..1564906(-) (covR) [Streptococcus canis strain HL_77_2]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKLPSQGIYRDLVLNPQNRSVNRGDDEIPLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=447225 GE022_RS07645 WP_003046762.1 1564220..1564906(-) (covR) [Streptococcus canis strain HL_77_2]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAAAATCTCGCAAGGTTTGTTTCACTTGAACTGCAACATGAAGGTTA
TGAAGTAACCGTTGAAGTAAATGGTCGTGAAGGGTTAGAAACTGCCTTGGAAAAGGATTTTGATTTAATTTTGCTTGACT
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACCCGTCGCTTACAGACTGAAAAAACAACATATATCATGATGATGACT
GCACGTGATTCGATTATGGATGTGGTGGCAGGCTTGGACCGTGGTGCGGATGACTATATTGTTAAGCCATTTGCGATTGA
AGAATTGTTGGCTCGTATTCGTGCAATTTTCCGTCGTCAAGATATTGAATCTGAAAAGAAACTGCCCAGTCAAGGAATTT
ATCGTGACTTGGTCTTGAACCCACAAAACCGTTCGGTTAATCGTGGGGATGATGAAATTCCCCTCACTAAACGTGAATAC
GACTTGCTTAGCATTTTGATGACAAACATGAACCGTGTGATGACACGTGAAGAATTGCTCTCAAATGTTTGGAAATATGA
TGAGGCAGTTGAAACAAACGTTGTTGATGTTTACATTCGTTACCTTCGTGGTAAAGTTGACATCCCAGGCAAGGAATCTT
ATATCCAAACCGTTCGCGGCATGGGATATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.103

100

0.439
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.421