Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GE023_RS07935 Genome accession   NZ_CP053789
Coordinates   1597789..1598475 (-) Length   228 a.a.
NCBI ID   WP_003046762.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_98_2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1592789..1603475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS07915 (GE023_007910) dnaI 1593512..1594414 (-) 903 WP_093998461.1 primosomal protein DnaI -
  GE023_RS07920 (GE023_007915) - 1594415..1595584 (-) 1170 WP_164406120.1 DnaD domain protein -
  GE023_RS07925 (GE023_007920) nrdR 1595568..1596062 (-) 495 WP_003046767.1 transcriptional regulator NrdR -
  GE023_RS07930 (GE023_007925) - 1596281..1597783 (-) 1503 WP_003046765.1 HAMP domain-containing histidine kinase -
  GE023_RS07935 (GE023_007930) covR 1597789..1598475 (-) 687 WP_003046762.1 two-component system response regulator CovR Regulator
  GE023_RS07940 (GE023_007935) - 1598736..1599269 (-) 534 WP_003046759.1 DUF177 domain-containing protein -
  GE023_RS07945 (GE023_007940) htpX 1599542..1600444 (-) 903 WP_099982901.1 zinc metalloprotease HtpX -
  GE023_RS07950 (GE023_007945) - 1600492..1601049 (-) 558 WP_003046754.1 LemA family protein -
  GE023_RS07955 (GE023_007950) rsmG 1601199..1601912 (+) 714 WP_093998466.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  GE023_RS07960 (GE023_007955) ktrB 1601993..1603369 (+) 1377 WP_003046748.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26575.63 Da        Isoelectric Point: 4.6541

>NTDB_id=447171 GE023_RS07935 WP_003046762.1 1597789..1598475(-) (covR) [Streptococcus canis strain HL_98_2]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKLPSQGIYRDLVLNPQNRSVNRGDDEIPLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=447171 GE023_RS07935 WP_003046762.1 1597789..1598475(-) (covR) [Streptococcus canis strain HL_98_2]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAAAATCTCGCAAGGTTTGTTTCACTTGAACTGCAACATGAAGGTTA
TGAAGTAACCGTTGAAGTAAATGGTCGTGAAGGGTTAGAAACTGCCTTGGAAAAGGATTTTGATTTAATCTTGCTTGACT
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACCCGTCGCTTACAGACTGAAAAAACAACATATATCATGATGATGACT
GCACGTGATTCGATTATGGATGTGGTGGCAGGCTTGGACCGTGGTGCGGATGACTATATTGTTAAGCCATTTGCGATTGA
AGAATTGTTGGCTCGTATTCGTGCAATTTTCCGTCGTCAAGATATTGAATCTGAAAAGAAACTGCCTAGTCAAGGAATTT
ATCGTGACTTGGTCTTGAACCCACAAAACCGTTCGGTTAATCGTGGGGATGATGAAATTCCCCTCACTAAACGTGAATAC
GACTTGCTTAGCATTTTGATGACAAACATGAACCGTGTGATGACACGTGAAGAATTGCTCTCAAATGTTTGGAAATATGA
TGAGGCAGTTGAAACAAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGTAAAGTTGACATCCCAGGTAAGGAATCTT
ATATCCAAACCGTTCGCGGCATGGGATATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.103

100

0.439
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.421