Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   I5V48_RS08015 Genome accession   NZ_CP065430
Coordinates   1699398..1700060 (-) Length   220 a.a.
NCBI ID   WP_172097433.1    Uniprot ID   -
Organism   Streptococcus suis strain YZDH1     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1694398..1705060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5V48_RS08010 (I5V48_08010) - 1697177..1699414 (-) 2238 Protein_1571 DNA internalization-related competence protein ComEC/Rec2 -
  I5V48_RS08015 (I5V48_08015) comEA/celA/cilE 1699398..1700060 (-) 663 WP_172097433.1 helix-hairpin-helix domain-containing protein Machinery gene
  I5V48_RS08020 (I5V48_08020) - 1700127..1700873 (-) 747 WP_043026932.1 lysophospholipid acyltransferase family protein -
  I5V48_RS08025 (I5V48_08025) - 1701022..1702467 (+) 1446 WP_043026933.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  I5V48_RS08030 (I5V48_08030) - 1702933..1703718 (+) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  I5V48_RS08035 (I5V48_08035) - 1703731..1704660 (+) 930 WP_029178642.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23454.03 Da        Isoelectric Point: 4.0498

>NTDB_id=447023 I5V48_RS08015 WP_172097433.1 1699398..1700060(-) (comEA/celA/cilE) [Streptococcus suis strain YZDH1]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFSQPQQSSSSQEQLEEVSTEESEESSQLVVDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSQDEKNTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANSGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=447023 I5V48_RS08015 WP_172097433.1 1699398..1700060(-) (comEA/celA/cilE) [Streptococcus suis strain YZDH1]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCAGCAGTGGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGCCAACCAGCTAAGTCTGATCAGACAGGCCTGACTGATTTTTCACAGCCACAGCAAA
GTTCAAGTAGTCAGGAGCAGCTTGAAGAAGTCAGTACAGAAGAAAGTGAAGAGTCGAGCCAGCTGGTCGTTGATGTCAAA
GGAGCGGTGGAAAAACCAGGGCTGTATACCTTAGAAGCTGGTGCGCGTGTCAATGATGCAGTAGAGGCAGCTGGCGGCTT
GACCAGTCAGGCAGATCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTAGTCTATGTGGCCAGCAAGG
ATGAAAATATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCCCAAGACGAAAAAAATACCAGTCTAGTCAAT
CTCAATACGGCTACCGAGGCTGATTTGCAGACCATTTCGGGCATCGGAGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCCAATAGTGGCTTCAAGTCGGTGGACGACCTCAACAATGTCTCGGGCATCGGCGACAAGACCATGGAAAGCATTC
GACCTTATGTCACGGTCGATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

45.815

100

0.473
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

45.815

100

0.473
  comEA/celA/cilE Streptococcus mitis SK321

46.396

100

0.468
  comEA/celA/cilE Streptococcus pneumoniae Rx1

46.575

99.545

0.464
  comEA/celA/cilE Streptococcus pneumoniae D39

46.575

99.545

0.464
  comEA/celA/cilE Streptococcus pneumoniae R6

46.575

99.545

0.464
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

38.249

98.636

0.377
  comEA Bacillus subtilis subsp. subtilis str. 168

38.278

95

0.364