Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HLY12_RS02090 Genome accession   NZ_CP053259
Coordinates   451163..452287 (+) Length   374 a.a.
NCBI ID   WP_001613939.1    Uniprot ID   -
Organism   Escherichia coli strain GF3-3     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 446163..457287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLY12_RS02065 (HLY12_02065) mscL 446289..446699 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  HLY12_RS02070 (HLY12_02070) trkA 446829..448205 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  HLY12_RS02075 (HLY12_02075) rsmB 448227..449516 (-) 1290 WP_001613941.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  HLY12_RS02080 (HLY12_02080) fmt 449562..450509 (-) 948 WP_001613940.1 methionyl-tRNA formyltransferase -
  HLY12_RS02085 (HLY12_02085) def 450524..451033 (-) 510 WP_000114984.1 peptide deformylase -
  HLY12_RS02090 (HLY12_02090) dprA 451163..452287 (+) 1125 WP_001613939.1 DNA-protecting protein DprA Machinery gene
  HLY12_RS02095 (HLY12_02095) smg 452259..452732 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  HLY12_RS02100 (HLY12_02100) yrdD 452761..453303 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  HLY12_RS02105 (HLY12_02105) tsaC 453308..453880 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  HLY12_RS02110 (HLY12_02110) aroE 453885..454703 (+) 819 WP_000451211.1 shikimate dehydrogenase -
  HLY12_RS02115 (HLY12_02115) yrdB 454700..454957 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  HLY12_RS02120 (HLY12_02120) yrdA 454933..455487 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41001.98 Da        Isoelectric Point: 6.4458

>NTDB_id=443805 HLY12_RS02090 WP_001613939.1 451163..452287(+) (dprA) [Escherichia coli strain GF3-3]
MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=443805 HLY12_RS02090 WP_001613939.1 451163..452287(+) (dprA) [Escherichia coli strain GF3-3]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCTGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAACGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCACTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGACCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCTTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (DprA_WH)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Haemophilus influenzae Rd KW20

45.401

90.107

0.409
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393