Detailed information NTG0443437

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: HKM25_RS04635
• Genome accession: NZ_CP053210
• Coordinates: 912524..913477 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 6A-10
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 907524..918477

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HKM25_RS04610	rpmG	908267..908416 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
HKM25_RS04615 (HKM25_945)	secG	908456..908689 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
HKM25_RS04620 (HKM25_946)	rnr	908791..911145 (+)	2355	WP_000654917.1	ribonuclease R	-
HKM25_RS04625 (HKM25_947)	smpB	911108..911575 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
HKM25_RS04630 (HKM25_948)	tehB	911591..912451 (+)	861	WP_000413773.1	SAM-dependent methyltransferase TehB	-
HKM25_RS04635 (HKM25_949)	coiA	912524..913477 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
HKM25_RS04640 (HKM25_950)	pepF	913496..915298 (+)	1803	WP_000244134.1	oligoendopeptidase F	Regulator
HKM25_RS04645 (HKM25_951)	-	915300..916013 (+)	714	WP_000230399.1	O-methyltransferase	-
HKM25_RS04650 (HKM25_952)	prsA	916080..917021 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
HKM25_RS04655 (HKM25_953)	-	917140..917481 (-)	342	Protein_935	IS3 family transposase	-
HKM25_RS04660	-	917897..917992 (+)	96	Protein_936	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=443437 HKM25_RS04635 WP_000495909.1 912524..913477(+) (coiA) [Streptococcus pneumoniae strain 6A-10]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=443437 HKM25_RS04635 WP_000495909.1 912524..913477(+) (coiA) [Streptococcus pneumoniae strain 6A-10]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435