Detailed information NTG0443324

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: IUJ54_RS05070
• Genome accession: NZ_CP064378
• Coordinates: 1179168..1179845 (+)
• Length: 225 a.a.
• NCBI ID: WP_011213604.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pneumophila strain PartS-Lpneumophila-RM8376
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1174168..1184845

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ54_RS05045 (IUJ54_05045)	-	1174664..1174873 (-)	210	WP_011213609.1	hypothetical protein	-
IUJ54_RS05050 (IUJ54_05050)	rlmJ	1175149..1175997 (+)	849	WP_015444565.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
IUJ54_RS05055 (IUJ54_05055)	gloB	1176001..1176765 (+)	765	WP_010947026.1	hydroxyacylglutathione hydrolase	-
IUJ54_RS05060 (IUJ54_05060)	-	1176880..1178319 (+)	1440	WP_010947025.1	LysM peptidoglycan-binding domain-containing protein	-
IUJ54_RS05065 (IUJ54_05065)	-	1178562..1179107 (+)	546	WP_010947024.1	septation protein A	-
IUJ54_RS05070 (IUJ54_05070)	ciaR	1179168..1179845 (+)	678	WP_011213604.1	response regulator	Regulator
IUJ54_RS05075 (IUJ54_05075)	-	1179842..1181257 (+)	1416	WP_010947022.1	ATP-binding protein	-
IUJ54_RS05080 (IUJ54_05080)	lem8	1181541..1183127 (+)	1587	WP_010947021.1	Dot/Icm T4SS effector Lem8	-
IUJ54_RS05085 (IUJ54_05085)	-	1183160..1183480 (-)	321	WP_010947020.1	hypothetical protein	-
IUJ54_RS05090 (IUJ54_05090)	ruvA	1183530..1184129 (-)	600	WP_010947019.1	Holliday junction branch migration protein RuvA	-
IUJ54_RS05095 (IUJ54_05095)	ruvC	1184126..1184650 (-)	525	WP_010947018.1	crossover junction endodeoxyribonuclease RuvC	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25151.74 Da
• Isoelectric Point: 4.9981

>NTDB_id=443324 IUJ54_RS05070 WP_011213604.1 1179168..1179845(+) (ciaR) [Legionella pneumophila subsp. pneumophila strain PartS-Lpneumophila-RM8376]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide

• Length: 678 bp

>NTDB_id=443324 IUJ54_RS05070 WP_011213604.1 1179168..1179845(+) (ciaR) [Legionella pneumophila subsp. pneumophila strain PartS-Lpneumophila-RM8376]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTAAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAGCCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTGGTAAGGCGCTCTCAGGGCAGAGCTGATTCCGTGTTGCAATATAAAAATATTACTC
TCGATCCTGCTGCTCATTCTGTCTTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGCCAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTCGAAGTTCATATACATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (148-215)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae D39	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae R6	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae TIGR4	38.356	97.333	0.373
ciaR	Streptococcus mutans UA159	37.9	97.333	0.369
micA	Streptococcus pneumoniae Cp1015	35.345	100	0.364