Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   HHM66_RS03015 Genome accession   NZ_CP053074
Coordinates   575469..576176 (+) Length   235 a.a.
NCBI ID   WP_003055001.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 570469..581176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM66_RS02995 (HHM66_03000) - 571182..572606 (+) 1425 WP_015057406.1 glycoside hydrolase family 1 protein -
  HHM66_RS03000 (HHM66_03005) - 572705..573520 (-) 816 WP_015057407.1 TIGR03943 family protein -
  HHM66_RS03005 (HHM66_03010) - 573520..574422 (-) 903 WP_015057408.1 permease -
  HHM66_RS10865 - 574569..574748 (-) 180 WP_206151251.1 SPJ_0845 family protein -
  HHM66_RS03010 (HHM66_03015) - 574900..575382 (+) 483 WP_015057410.1 cupin domain-containing protein -
  HHM66_RS03015 (HHM66_03020) vicR 575469..576176 (+) 708 WP_003055001.1 response regulator transcription factor Regulator
  HHM66_RS03020 (HHM66_03025) - 576177..577505 (+) 1329 WP_015057411.1 ATP-binding protein -
  HHM66_RS03025 (HHM66_03030) - 577672..578547 (+) 876 WP_014612110.1 substrate-binding domain-containing protein -
  HHM66_RS03030 (HHM66_03035) pstC 578665..579528 (+) 864 WP_012766699.1 phosphate ABC transporter permease subunit PstC -
  HHM66_RS03035 (HHM66_03040) pstA 579521..580336 (+) 816 WP_015057412.1 phosphate ABC transporter permease PstA -
  HHM66_RS03040 (HHM66_03045) pstB 580338..581090 (+) 753 WP_003055005.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27491.70 Da        Isoelectric Point: 5.4461

>NTDB_id=442774 HHM66_RS03015 WP_003055001.1 575469..576176(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MTKQILLVDDEEHILRLLDYHLGKEGFSTQLVTDGRKALTLAETEPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAILRRTSKEQQEDDTDDFRDDYRVFGALTVYPDRHEVYKADHLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDNPKDPQFIQTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=442774 HHM66_RS03015 WP_003055001.1 575469..576176(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
ATGACAAAACAAATCTTATTAGTGGATGATGAAGAACACATTTTGAGGCTACTGGATTATCATCTCGGTAAAGAAGGGTT
TTCCACACAATTGGTAACAGATGGCCGAAAAGCATTGACATTGGCAGAAACAGAGCCTTTTGACTTTATCCTACTGGATA
TTATGTTGCCTCAGTTAGACGGCATAGAAGTGTGTAAGCGACTGAGAGCTAAAGGAATAAAAACTCCGATTATGATGGTT
TCTGCTAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGAGCTGATGACTACCTGACTAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTATTTTACGTCGAACCAGTAAAGAGCAGCAAGAAGATGACACAGATGATTTCA
GGGATGATTATCGGGTATTTGGGGCCCTGACCGTCTATCCAGACCGGCATGAGGTTTATAAGGCAGATCATTTATTGAGC
CTTACCCCAAAGGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACATTAACTAGGGAACGTTTACTTGA
ACGGATTTGGGGATATGATTTTGGACAAGAAACCCGTTTAGTGGATGTTCATATTGGCAAATTGAGAGATAAGATAGAGG
ATAATCCTAAAGACCCTCAATTTATTCAAACGATTAGAGGCTATGGGTATAAGTTTAAGGAGTTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

49.145

99.574

0.489
  micA Streptococcus pneumoniae Cp1015

47.619

98.298

0.468
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.772

100

0.421
  covR Streptococcus salivarius strain HSISS4

40.506

100

0.409