Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HHM66_RS02070 Genome accession   NZ_CP053074
Coordinates   388962..389648 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 383962..394648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM66_RS02045 (HHM66_02050) ktrB 384068..385444 (-) 1377 WP_015057340.1 potassium uptake transporter channel subunit KtrB -
  HHM66_RS02050 (HHM66_02055) rsmG 385528..386241 (-) 714 WP_003058986.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  HHM66_RS02055 (HHM66_02060) - 386394..386951 (+) 558 WP_003058947.1 LemA family protein -
  HHM66_RS02060 (HHM66_02065) htpX 386998..387891 (+) 894 WP_003059035.1 zinc metalloprotease HtpX -
  HHM66_RS02065 (HHM66_02070) - 388158..388691 (+) 534 WP_014612038.1 DUF177 domain-containing protein -
  HHM66_RS02070 (HHM66_02075) covR 388962..389648 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  HHM66_RS02075 (HHM66_02080) - 389654..391153 (+) 1500 WP_003058944.1 HAMP domain-containing histidine kinase -
  HHM66_RS02080 (HHM66_02085) nrdR 391359..391853 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  HHM66_RS02085 (HHM66_02090) - 391837..393015 (+) 1179 WP_012766597.1 DnaD domain protein -
  HHM66_RS02090 (HHM66_02095) dnaI 393016..393918 (+) 903 WP_015057342.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=442766 HHM66_RS02070 WP_003049736.1 388962..389648(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=442766 HHM66_RS02070 WP_003049736.1 388962..389648(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425