Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   HMPREF1038_RS00135 Genome accession   NC_018630
Coordinates   22364..22600 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae gamPNI0373     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 17364..27600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS11145 - 20422..21268 (+) 847 Protein_14 IS630 family transposase -
  HMPREF1038_RS11150 - 21303..22100 (-) 798 Protein_15 transposase -
  HMPREF1038_RS00135 (HMPREF1038_00022) comW 22364..22600 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  HMPREF1038_RS00140 (HMPREF1038_00023) - 22831..24117 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  HMPREF1038_RS00145 (HMPREF1038_00024) - 24349..25497 (-) 1149 WP_000876726.1 site-specific integrase -
  HMPREF1038_RS00150 (HMPREF1038_00025) - 25672..26484 (-) 813 WP_001174227.1 HIRAN domain-containing protein -
  HMPREF1038_RS12180 - 26522..26902 (-) 381 Protein_20 ImmA/IrrE family metallo-endopeptidase -
  HMPREF1038_RS00160 (HMPREF1038_00028) - 26915..27178 (-) 264 WP_000285962.1 type II toxin-antitoxin system RelE/ParE family toxin -
  HMPREF1038_RS00165 (HMPREF1038_00029) - 27178..27411 (-) 234 WP_000156422.1 hypothetical protein -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=44160 HMPREF1038_RS00135 WP_000939546.1 22364..22600(+) (comW) [Streptococcus pneumoniae gamPNI0373]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=44160 HMPREF1038_RS00135 WP_000939546.1 22364..22600(+) (comW) [Streptococcus pneumoniae gamPNI0373]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987
  comW Streptococcus pneumoniae D39

98.718

100

0.987
  comW Streptococcus pneumoniae R6

98.718

100

0.987
  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756

Multiple sequence alignment