Detailed information NTG0441246

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: HIN87_RS10915
• Genome accession: NZ_CP051869
• Coordinates: 2248334..2249452 (-)
• Length: 372 a.a.
• NCBI ID: WP_000347036.1
• Uniprot ID: A0A009PAD6
• Organism: Acinetobacter baumannii strain Ab-D10a-a
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2243334..2254452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HIN87_RS10885 (HIN87_10885)	-	2244164..2245012 (+)	849	WP_000336551.1	class II glutamine amidotransferase	-
HIN87_RS10890 (HIN87_10890)	-	2245264..2245719 (+)	456	WP_000782976.1	bacteriohemerythrin	-
HIN87_RS10895 (HIN87_10895)	-	2245872..2246939 (+)	1068	WP_004748097.1	hypothetical protein	-
HIN87_RS10900 (HIN87_10900)	-	2246939..2247262 (+)	324	WP_032000562.1	RnfH family protein	-
HIN87_RS10905 (HIN87_10905)	-	2247317..2247715 (-)	399	WP_001170994.1	outer membrane protein assembly factor BamE	-
HIN87_RS10910 (HIN87_10910)	fur	2247827..2248264 (+)	438	WP_001122847.1	ferric iron uptake transcriptional regulator	-
HIN87_RS10915 (HIN87_10915)	pilU	2248334..2249452 (-)	1119	WP_000347036.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
HIN87_RS10920 (HIN87_10920)	pilT	2249480..2250517 (-)	1038	WP_000355489.1	type IV pilus twitching motility protein PilT	Machinery gene
HIN87_RS10925 (HIN87_10925)	-	2250644..2251336 (+)	693	WP_032000563.1	YggS family pyridoxal phosphate-dependent enzyme	-

Sequence

Protein

• Length: 372 a.a.
• Molecular weight: 41905.11 Da
• Isoelectric Point: 6.6944

>NTDB_id=441246 HIN87_RS10915 WP_000347036.1 2248334..2249452(-) (pilU) [Acinetobacter baumannii strain Ab-D10a-a]
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRKEFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ

Nucleotide

• Length: 1119 bp

>NTDB_id=441246 HIN87_RS10915 WP_000347036.1 2248334..2249452(-) (pilU) [Acinetobacter baumannii strain Ab-D10a-a]
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACCGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAATAGTCTTTCTGGGGAAGTAATTGGTCAACTGTTACATTCCA
TCATGAGTGAAAAACAACGCAAAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAACGCGACATGCCAGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCACCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTCGTAGGCGCGACAG
GCACAGGTAAATCTACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCTGATGAGGGTCCTGATCAATTATCAGACGGAAAGCAGCATTTAACTTTTGACCGCCAGTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (31-270)

3D structure

• AlphaFold DB: A0A009PAD6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	75.926	100	0.772
pilU	Pseudomonas stutzeri DSM 10701	69.293	98.925	0.685
pilU	Vibrio cholerae strain A1552	53.243	99.462	0.53
pilT	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	42.197	93.011	0.392