Detailed information NTG0440138

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: HHJ57_RS01660
• Genome accession: NZ_CP051641
• Coordinates: 308759..310081 (+)
• Length: 440 a.a.
• NCBI ID: WP_035688106.1
• Uniprot ID: -
• Organism: Avibacterium paragallinarum strain ADL-AP02
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	298117..308750	308759..310081	flank	9

Gene organization within MGE regions

Location: 298117..310081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHJ57_RS01610 (HHJ57_01610)	-	298117..298722 (+)	606	WP_035688088.1	hypothetical protein	-
HHJ57_RS01615 (HHJ57_01615)	glyS	298748..300811 (+)	2064	WP_035688090.1	glycine--tRNA ligase subunit beta	-
HHJ57_RS01620 (HHJ57_01620)	-	300930..301358 (-)	429	WP_017806833.1	Rrf2 family transcriptional regulator	-
HHJ57_RS01625 (HHJ57_01625)	hmpA	301497..302696 (+)	1200	WP_035688092.1	NO-inducible flavohemoprotein	-
HHJ57_RS01630 (HHJ57_01630)	-	302940..303593 (-)	654	WP_035688094.1	IS1595 family transposase	-
HHJ57_RS01635 (HHJ57_01635)	-	303860..306409 (-)	2550	WP_035688097.1	penicillin-binding protein 1A	-
HHJ57_RS01640 (HHJ57_01640)	-	306568..307335 (+)	768	WP_035688099.1	hypothetical protein	-
HHJ57_RS01645 (HHJ57_01645)	-	307365..307877 (+)	513	WP_046097217.1	PilN domain-containing protein	-
HHJ57_RS01650 (HHJ57_01650)	-	307870..308391 (+)	522	WP_124994794.1	hypothetical protein	-
HHJ57_RS01655 (HHJ57_01655)	-	308391..308750 (+)	360	WP_017806828.1	hypothetical protein	-
HHJ57_RS01660 (HHJ57_01660)	comE	308759..310081 (+)	1323	WP_035688106.1	type IV pilus secretin PilQ	Machinery gene

Sequence

Protein

• Length: 440 a.a.
• Molecular weight: 48606.59 Da
• Isoelectric Point: 6.1204

>NTDB_id=440138 HHJ57_RS01660 WP_035688106.1 308759..310081(+) (comE) [Avibacterium paragallinarum strain ADL-AP02]
MKLPNIIKNILLFFLILSYPFRQVNASDENNTFSVHLKQAPLVDTVQYLAGYQKINLVIDDELSGSISLQLQNTTLLQLL
KSIAEIKHLRFWENNGIYYLSQSQATNQENVVLNSSTEIATSADMLITSIKLHYAKASEVMKALTSGNGSLLTANGSISF
DERNNLLIIQDEAKKIKQIRKLVADMDKPIQQIIIEARIVTISDESLKELGVRWGIFSPSDISHSVSGSLNANGFSNITD
NLNINFATSSNPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVNNGKNDTQSIE
FREAVLGLEVTPHLLKHNGILLDLVVSQNAPGGRVSYGENEVISIDKQEINTQVFAQDGETIVLGGIFHDTITKALDKVP
ILGDIPGIKRLFSKEVERHQKRELVIFVTPRLIRSGTVEE

Nucleotide

• Length: 1323 bp

>NTDB_id=440138 HHJ57_RS01660 WP_035688106.1 308759..310081(+) (comE) [Avibacterium paragallinarum strain ADL-AP02]
ATGAAGTTACCAAATATAATAAAGAATATTCTTTTATTTTTTCTTATTCTATCCTATCCATTTAGACAGGTTAATGCAAG
TGACGAAAATAATACATTCTCTGTTCATTTAAAGCAGGCTCCATTAGTAGATACTGTACAATATTTAGCTGGGTATCAAA
AAATCAATTTAGTCATAGATGATGAATTGTCTGGTTCAATATCTTTGCAATTGCAAAATACAACATTACTTCAATTATTA
AAATCTATCGCTGAAATCAAACATTTGCGGTTTTGGGAAAATAATGGGATATATTATTTAAGTCAGTCGCAAGCAACTAA
TCAAGAAAATGTAGTGTTAAATTCATCAACAGAAATAGCAACATCAGCAGATATGTTAATAACTTCAATAAAGTTGCACT
ATGCCAAAGCATCCGAGGTAATGAAAGCCCTCACTTCAGGGAATGGCTCTTTATTAACAGCAAATGGAAGTATAAGTTTT
GATGAACGCAATAATTTACTCATTATCCAAGATGAAGCTAAAAAAATAAAACAAATTAGGAAATTGGTAGCGGATATGGA
TAAACCCATTCAGCAAATTATTATTGAAGCTCGTATTGTCACAATTAGCGATGAAAGTTTAAAAGAATTGGGAGTCAGAT
GGGGAATTTTTTCTCCCTCAGATATAAGCCATAGCGTTTCTGGAAGTTTAAATGCAAATGGATTCTCAAATATTACGGAT
AATCTAAATATTAATTTTGCGACGAGTTCAAATCCTGCAGGTTCGGTAGCTTTGCAAGTAGCTAAAATTAATGGAAGGTT
ATTAGATTTAGAGTTGACAGCATTAGAAAGAGAAAATAACGTTGAAATTATTGCGAGTCCACGATTATTGACCACAAATA
AGAAAAGTGCAAGTATCAAGCAAGGTACAGAAATCCCCTATGTAGTGAATAATGGAAAAAATGATACGCAGTCTATTGAA
TTCCGAGAAGCTGTACTTGGGCTTGAAGTTACACCTCATTTATTAAAGCATAACGGTATTTTACTTGATCTTGTTGTTAG
TCAGAATGCACCTGGAGGACGAGTATCTTATGGAGAAAATGAGGTGATTTCTATTGATAAACAGGAAATTAATACGCAAG
TCTTTGCACAAGACGGCGAAACGATTGTATTGGGCGGAATTTTCCACGATACGATTACTAAAGCACTTGATAAAGTACCA
ATTTTAGGAGACATACCTGGAATAAAAAGGCTATTTAGTAAGGAAGTCGAGAGACATCAAAAGAGGGAACTCGTTATTTT
TGTTACACCACGCTTAATTCGTAGTGGTACAGTAGAGGAATGA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (129-192)

• Bacterial type II and III secretion system protein (Secretin) (274-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	65.023	96.818	0.63
comE	Haemophilus influenzae 86-028NP	64.789	96.818	0.627
comE	Glaesserella parasuis strain SC1401	49.883	97.045	0.484
pilQ	Vibrio campbellii strain DS40M4	40	96.591	0.386
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	40.288	94.773	0.382
pilQ	Vibrio cholerae strain A1552	40.288	94.773	0.382