Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   IM723_RS08155 Genome accession   NZ_CP063275
Coordinates   1578150..1579517 (-) Length   455 a.a.
NCBI ID   WP_084829837.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain DMST-H2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1573150..1584517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IM723_RS08130 - 1573500..1573766 (-) 267 WP_211836860.1 Blp family class II bacteriocin -
  IM723_RS10340 - 1574017..1574418 (-) 402 WP_011226490.1 hypothetical protein -
  IM723_RS08135 - 1575405..1575635 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  IM723_RS08140 comE/blpR 1575885..1576616 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  IM723_RS10100 comD/blpH 1577153..1577956 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  IM723_RS08150 - 1577974..1578135 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  IM723_RS08155 comB 1578150..1579517 (-) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator
  IM723_RS08160 comA/nlmT 1579533..1581623 (-) 2091 WP_232974663.1 peptide cleavage/export ABC transporter Regulator
  IM723_RS08165 - 1582700..1584445 (-) 1746 WP_024703994.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50399.10 Da        Isoelectric Point: 4.7492

>NTDB_id=437776 IM723_RS08155 WP_084829837.1 1578150..1579517(-) (comB) [Streptococcus thermophilus strain DMST-H2]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLESRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=437776 IM723_RS08155 WP_084829837.1 1578150..1579517(-) (comB) [Streptococcus thermophilus strain DMST-H2]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAAGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.246

99.121

0.389
  comB Streptococcus pneumoniae D39

39.246

99.121

0.389
  comB Streptococcus pneumoniae R6

39.246

99.121

0.389
  comB Streptococcus pneumoniae TIGR4

38.581

99.121

0.382
  comB Streptococcus mitis SK321

37.916

99.121

0.376
  comB Streptococcus mitis NCTC 12261

37.916

99.121

0.376