Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   IM723_RS03550 Genome accession   NZ_CP063275
Coordinates   667015..668376 (-) Length   453 a.a.
NCBI ID   WP_173940475.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain DMST-H2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 662015..673376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IM723_RS03530 - 664279..664620 (+) 342 WP_024404826.1 LytTR family DNA-binding domain-containing protein -
  IM723_RS03535 comE/blpR 664622..665362 (+) 741 WP_096811959.1 response regulator transcription factor Regulator
  IM723_RS03540 - 665373..666713 (+) 1341 WP_039671036.1 GHKL domain-containing protein -
  IM723_RS03545 - 666761..666916 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  IM723_RS03550 comB 667015..668376 (-) 1362 WP_173940475.1 bacteriocin secretion accessory protein Regulator
  IM723_RS03555 comA/nlmT 668388..670541 (-) 2154 WP_039671034.1 peptide cleavage/export ABC transporter Regulator
  IM723_RS03560 - 670838..671092 (+) 255 WP_039671033.1 Blp family class II bacteriocin -
  IM723_RS03565 - 671107..671310 (+) 204 WP_039671032.1 Blp family class II bacteriocin -
  IM723_RS03570 - 671824..672108 (-) 285 Protein_645 transposase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 50371.48 Da        Isoelectric Point: 5.2958

>NTDB_id=437736 IM723_RS03550 WP_173940475.1 667015..668376(-) (comB) [Streptococcus thermophilus strain DMST-H2]
MNPNLFKSAEFYQRRYHNFATHLIVPLILLVGFLLTFSLFAQKEVTVTSRGEITPTTIIASIQSTSNNPITTNNLANNKL
VKKNELIIQYAETMESSQKQALETQLATLNRQKTGLETLKESLSQGTNLFTGEDEFGYINTFNNFITQSQDIELGISKTN
AEVSNQAALAGNTIAAIDTQINQIYHQIAEYEELRQAITNRQTSLSADNPHQGTLNNFLAQSQQDSQTGLTDQYLFQINQ
SISGLESSIASLNIQRAGTGSVATYDNSFVTKVEVLRTQFLQSASQQLTTLETQITELVAQLEQASVRLENNTITAPETG
VIHLNSEFEGKSLIPSGSEIAQIYPNINQTKEFLITYYVTSEHVALLKEKQDVRLSLEKVGNQSITVVGKIKSIDKTATK
TEEGNLFKVTALAQLSDKHSDVIQYGLQGRVTSIIAKKTYFDYYKDKILSNHD

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=437736 IM723_RS03550 WP_173940475.1 667015..668376(-) (comB) [Streptococcus thermophilus strain DMST-H2]
ATGAACCCTAATTTGTTCAAAAGTGCTGAATTTTACCAGCGGCGCTACCATAATTTTGCGACACACTTAATTGTCCCCTT
GATATTATTAGTCGGCTTTCTTCTAACCTTCTCCCTTTTTGCCCAAAAGGAGGTTACCGTCACATCAAGAGGTGAAATTA
CTCCGACGACAATCATCGCTTCCATCCAATCCACCAGCAATAACCCTATCACAACCAATAATCTAGCCAATAACAAGCTG
GTTAAAAAGAATGAGCTCATCATCCAATACGCTGAAACTATGGAGAGTTCCCAAAAACAAGCCCTTGAAACCCAGCTAGC
CACTCTAAATAGACAGAAAACTGGACTTGAAACCCTCAAAGAAAGCCTGTCACAGGGAACGAACCTCTTTACAGGGGAGG
ACGAATTTGGCTATATCAATACTTTTAACAACTTTATCACCCAGTCACAGGACATCGAACTAGGAATTTCCAAAACCAAT
GCAGAGGTGAGTAACCAGGCCGCCCTAGCAGGTAATACCATTGCTGCGATTGACACGCAAATCAATCAAATCTATCACCA
AATAGCAGAATACGAGGAGCTTCGTCAAGCCATTACCAATAGACAGACCAGTTTATCAGCTGACAATCCACACCAAGGCA
CCTTAAACAATTTCTTAGCCCAATCCCAACAAGACTCCCAGACAGGATTAACTGATCAATACCTTTTTCAAATCAACCAA
AGTATCTCAGGGCTAGAATCATCCATAGCTAGTCTGAACATCCAACGAGCTGGAACTGGCTCTGTTGCAACCTATGATAA
CAGCTTTGTAACAAAGGTTGAGGTCCTAAGAACACAGTTTTTACAATCGGCCTCTCAGCAGCTGACCACCCTTGAAACGC
AAATCACAGAGCTAGTGGCACAGCTAGAGCAAGCATCCGTCCGACTAGAAAACAATACCATTACAGCTCCTGAAACAGGG
GTAATCCATCTCAATAGTGAGTTTGAAGGAAAGTCTTTGATTCCAAGCGGTAGTGAAATCGCTCAGATTTACCCCAATAT
CAATCAAACCAAAGAATTCCTCATTACTTACTACGTGACTTCAGAACATGTCGCCTTACTCAAAGAAAAACAAGACGTAC
GCCTGAGCTTAGAAAAAGTTGGCAACCAAAGCATCACTGTTGTTGGAAAAATTAAGTCTATCGATAAAACTGCTACTAAA
ACTGAGGAGGGGAATCTTTTCAAAGTTACTGCCTTGGCTCAACTATCCGACAAGCATAGCGACGTCATCCAGTACGGTCT
CCAGGGTCGAGTCACAAGTATCATTGCCAAGAAGACTTACTTTGATTACTACAAGGATAAAATTTTATCCAACCATGATT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(313-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

38.444

99.338

0.382
  comB Streptococcus pneumoniae D39

38.444

99.338

0.382
  comB Streptococcus pneumoniae R6

38.444

99.338

0.382
  comB Streptococcus pneumoniae TIGR4

38.222

99.338

0.38
  comB Streptococcus mitis SK321

37.639

99.117

0.373
  comB Streptococcus mitis NCTC 12261

37.639

99.117

0.373