Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HFV09_RS08030 Genome accession   NZ_CP051138
Coordinates   1589638..1590324 (-) Length   228 a.a.
NCBI ID   WP_002991052.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 4063-05     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1584638..1595324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HFV09_RS08010 dnaI 1585359..1586261 (-) 903 WP_011528269.1 primosomal protein DnaI -
  HFV09_RS08015 - 1586262..1587437 (-) 1176 WP_002991019.1 replication initiation and membrane attachment family protein -
  HFV09_RS08020 nrdR 1587421..1587915 (-) 495 WP_002985941.1 transcriptional regulator NrdR -
  HFV09_RS08025 covS 1588130..1589569 (-) 1440 WP_254595994.1 two-component system sensor histidine kinase CovS -
  HFV09_RS08030 covR 1589638..1590324 (-) 687 WP_002991052.1 two-component system response regulator CovR Regulator
  HFV09_RS08035 - 1590591..1591124 (-) 534 WP_011054200.1 DUF177 domain-containing protein -
  HFV09_RS08040 htpX 1591358..1592254 (-) 897 WP_002985953.1 zinc metalloprotease HtpX -
  HFV09_RS08045 - 1592301..1592858 (-) 558 WP_002985956.1 LemA family protein -
  HFV09_RS08050 rsmG 1593008..1593721 (+) 714 WP_011528267.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  HFV09_RS08055 ktrB 1593805..1595181 (+) 1377 WP_032459855.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26618.70 Da        Isoelectric Point: 4.6586

>NTDB_id=436182 HFV09_RS08030 WP_002991052.1 1589638..1590324(-) (covR) [Streptococcus pyogenes strain 4063-05]
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=436182 HFV09_RS08030 WP_002991052.1 1589638..1590324(-) (covR) [Streptococcus pyogenes strain 4063-05]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAATCTGGCTAGATTCGTTTCTCTTGAGCTGCAACATGAGGGTTA
TGAAGTCATTGTTGAGGTCAATGGTCGCGAAGGGTTAGAAACTGCTTTGGAAAAAGAGTTTGATTTAATCCTGCTTGACT
TAATGTTACCAGAGATGGATGGTTTTGAAGTGACCCGTCGTTTGCAAACCGAAAAAACAACATATATCATGATGATGACT
GCGCGTGATTCTATTATGGATGTGGTTGCAGGTTTAGACCGCGGTGCAGACGACTATATTGTTAAACCGTTTGCCATTGA
AGAACTACTTGCCCGTATTCGTGCTATTTTCCGCCGTCAAGACATTGAATCTGAGAAGAAAGTGCCTAGTCAAGGCATTT
ATCGAGATCTAGTTTTAAATCCACAAAACCGTTCAGTTAATCGTGGCGACGATGAGATTTCTCTCACTAAACGTGAATAT
GATTTGCTTAATATTTTGATGACTAACATGAATCGTGTCATGACACGTGAAGAATTATTGTCAAATGTTTGGAAATATGA
TGAAGCCGTTGAGACTAATGTTGTAGATGTCTATATTCGTTATCTCCGCGGCAAAATTGACATTCCAGGCAAGGAATCTT
ATATCCAAACAGTGCGTGGCATGGGATACGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.966

100

0.447
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425