Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   IMO23_RS14335 Genome accession   NZ_CP062919
Coordinates   2977589..2978263 (-) Length   224 a.a.
NCBI ID   WP_016653620.1    Uniprot ID   A0A7S8WCK1
Organism   Acinetobacter baumannii strain Res13-Abat-PEA21-P4-01-A     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2972589..2983263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMO23_RS14315 (IMO23_14315) - 2973003..2973887 (+) 885 WP_000144741.1 LysR family transcriptional regulator -
  IMO23_RS14320 (IMO23_14320) - 2974190..2975377 (+) 1188 WP_001181775.1 ammonium transporter -
  IMO23_RS14325 (IMO23_14325) - 2975530..2976228 (+) 699 WP_195707607.1 phosphatase PAP2 family protein -
  IMO23_RS14330 (IMO23_14330) - 2976229..2977563 (-) 1335 WP_000559381.1 two-component system sensor histidine kinase PmrB -
  IMO23_RS14335 (IMO23_14335) ciaR 2977589..2978263 (-) 675 WP_016653620.1 DNA-binding response regulator PmrA Regulator
  IMO23_RS14340 (IMO23_14340) - 2978278..2979927 (-) 1650 WP_114183583.1 phosphoethanolamine transferase -
  IMO23_RS14345 (IMO23_14345) - 2980109..2981440 (-) 1332 WP_195707608.1 DcaP family trimeric outer membrane transporter -
  IMO23_RS14350 (IMO23_14350) - 2981986..2983233 (-) 1248 WP_195707609.1 MFS transporter -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25575.50 Da        Isoelectric Point: 5.3246

>NTDB_id=435843 IMO23_RS14335 WP_016653620.1 2977589..2978263(-) (ciaR) [Acinetobacter baumannii strain Res13-Abat-PEA21-P4-01-A]
MTKILMIEDDFMIAESTITLLQYHQFEVEWVNNGLDGLAQLAKTKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLANQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=435843 IMO23_RS14335 WP_016653620.1 2977589..2978263(-) (ciaR) [Acinetobacter baumannii strain Res13-Abat-PEA21-P4-01-A]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGATCACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCTCAATTGGCGAAGACTAAATTTGATCTTATTCTTTTGGATTTAG
GATTGCCTATGATGGATGGTATGCAAGTTTTGAAGCAGATCCGTCAAAGAGCAGCAACACCAGTATTAATTATTTCTGCT
CGAGATCAATTACAAAACCGTGTCGATGGTTTAAATTTGGGTGCAGATGATTATTTAATTAAACCTTATGAATTTGATGA
GTTGCTTGCCCGTATTCATGCATTACTACGCCGTAGTGGAGTAGAAGCTCAACTTGCGAATCAAGATCAACTATTAGAAA
GTGGTGATCTGGTTTTAAATGTTGAACAGCATATTGCGACGTTTAAAGGTCAACGCATTGATCTATCAAATCGTGAATGG
GCAATCTTAATTCCACTTATGACTCACCCAAATAAAATCTTTTCTAAAGCCAACTTAGAAGATAAGTTATATGATTTTGA
TAGTGATGTGACCAGTAATACTATTGAAGTATATGTTCACCATTTAAGAGCGAAGCTGGGTAAAGATTTTATTCGAACCA
TCCGAGGACTGGGCTATCGTTTGGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 7M0S

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.885

100

0.384
  micA Streptococcus pneumoniae Cp1015

35.526

100

0.362