Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiC   Type   Regulator
Locus tag   HEQ84_RS06815 Genome accession   NZ_CP050870
Coordinates   1318591..1320084 (-) Length   497 a.a.
NCBI ID   WP_011681416.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS6     
Function   internalize XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1300117..1371150 1318591..1320084 within 0


Gene organization within MGE regions


Location: 1300117..1371150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HEQ84_RS06725 (HEQ84_06740) liaF 1300125..1300823 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  HEQ84_RS06730 - 1301078..1301245 (-) 168 WP_014608530.1 potassium channel family protein -
  HEQ84_RS06735 (HEQ84_06750) stkP/pknB 1301883..1303754 (-) 1872 WP_024703938.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HEQ84_RS06740 (HEQ84_06755) - 1303754..1304491 (-) 738 WP_002946881.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HEQ84_RS06745 (HEQ84_06760) rsmB 1304535..1305857 (-) 1323 WP_014608533.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  HEQ84_RS06750 (HEQ84_06765) fmt 1305847..1306782 (-) 936 WP_014608534.1 methionyl-tRNA formyltransferase -
  HEQ84_RS06755 (HEQ84_06770) - 1306800..1309196 (-) 2397 WP_024703939.1 primosomal protein N' -
  HEQ84_RS06760 (HEQ84_06775) rpoZ 1309338..1309652 (-) 315 WP_002951415.1 DNA-directed RNA polymerase subunit omega -
  HEQ84_RS06765 (HEQ84_06780) gmk 1309674..1310303 (-) 630 WP_014608537.1 guanylate kinase -
  HEQ84_RS06770 (HEQ84_06785) ftsY 1310529..1311920 (-) 1392 WP_014608538.1 signal recognition particle-docking protein FtsY -
  HEQ84_RS06775 (HEQ84_06790) - 1311934..1312749 (-) 816 WP_011226298.1 Cof-type HAD-IIB family hydrolase -
  HEQ84_RS06780 (HEQ84_06795) - 1312742..1313536 (-) 795 WP_011681412.1 HAD family hydrolase -
  HEQ84_RS06785 (HEQ84_06800) - 1313721..1314098 (+) 378 WP_011681413.1 GntR family transcriptional regulator -
  HEQ84_RS06790 (HEQ84_06805) - 1314103..1314801 (+) 699 WP_023909821.1 ABC transporter ATP-binding protein -
  HEQ84_RS06795 (HEQ84_06810) - 1314813..1315598 (+) 786 WP_002951425.1 hypothetical protein -
  HEQ84_RS06800 (HEQ84_06815) amiF 1315648..1316577 (-) 930 WP_002951426.1 ATP-binding cassette domain-containing protein Regulator
  HEQ84_RS06805 (HEQ84_06820) amiE 1316570..1317655 (-) 1086 WP_011226304.1 ABC transporter ATP-binding protein Regulator
  HEQ84_RS06810 (HEQ84_06825) amiD 1317665..1318591 (-) 927 WP_002946409.1 oligopeptide ABC transporter permease OppC Regulator
  HEQ84_RS06815 (HEQ84_06830) amiC 1318591..1320084 (-) 1494 WP_011681416.1 ABC transporter permease Regulator
  HEQ84_RS06820 (HEQ84_06835) amiA 1320146..1322113 (-) 1968 WP_024703940.1 peptide ABC transporter substrate-binding protein Regulator
  HEQ84_RS06825 - 1322469..1323646 (+) 1178 Protein_1300 ISL3 family transposase -
  HEQ84_RS06830 (HEQ84_06845) amiA3 1323691..1325664 (-) 1974 WP_011681419.1 peptide ABC transporter substrate-binding protein Regulator
  HEQ84_RS06835 (HEQ84_06850) - 1325969..1327116 (+) 1148 WP_095559415.1 IS3 family transposase -
  HEQ84_RS06840 (HEQ84_06855) - 1327154..1327338 (-) 185 Protein_1303 IS3 family transposase -
  HEQ84_RS06845 - 1327332..1327733 (-) 402 Protein_1304 ABC transporter ATP-binding protein -
  HEQ84_RS06850 (HEQ84_06870) - 1327728..1328088 (-) 361 Protein_1305 TatD family hydrolase -
  HEQ84_RS06855 (HEQ84_06875) - 1328434..1329639 (+) 1206 WP_011681420.1 OFA family MFS transporter -
  HEQ84_RS06860 (HEQ84_06880) - 1329685..1330998 (-) 1314 Protein_1307 IS3 family transposase -
  HEQ84_RS06865 (HEQ84_06885) pta 1331123..1332106 (-) 984 WP_011227420.1 phosphate acetyltransferase -
  HEQ84_RS06870 (HEQ84_06890) - 1332120..1333016 (-) 897 WP_024703943.1 RluA family pseudouridine synthase -
  HEQ84_RS06875 (HEQ84_06895) - 1333013..1333849 (-) 837 WP_014608552.1 NAD kinase -
  HEQ84_RS06880 (HEQ84_06900) - 1333821..1334495 (-) 675 WP_011681427.1 GTP pyrophosphokinase family protein -
  HEQ84_RS06885 (HEQ84_06905) - 1334591..1335166 (+) 576 WP_002951444.1 CYTH domain-containing protein -
  HEQ84_RS06890 (HEQ84_06910) - 1335529..1336500 (+) 972 WP_002951446.1 ribose-phosphate diphosphokinase -
  HEQ84_RS06895 (HEQ84_06915) - 1336504..1337616 (+) 1113 WP_014608554.1 cysteine desulfurase family protein -
  HEQ84_RS06900 (HEQ84_06920) - 1337618..1337965 (+) 348 WP_014608555.1 DUF1831 domain-containing protein -
  HEQ84_RS06905 (HEQ84_06925) - 1338109..1338768 (+) 660 WP_024703944.1 redox-sensing transcriptional repressor Rex -
  HEQ84_RS06910 (HEQ84_06930) - 1338761..1339456 (+) 696 WP_024703945.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  HEQ84_RS06915 (HEQ84_06935) radC 1339509..1340195 (-) 687 WP_014727630.1 DNA repair protein RadC -
  HEQ84_RS06920 (HEQ84_06940) - 1340244..1342028 (-) 1785 WP_024703946.1 rhamnan synthesis F family protein -
  HEQ84_RS06925 (HEQ84_06945) - 1342025..1343092 (-) 1068 WP_024703947.1 glycosyltransferase -
  HEQ84_RS06930 (HEQ84_06950) - 1343112..1344317 (-) 1206 WP_014727633.1 ABC transporter ATP-binding protein -
  HEQ84_RS06935 (HEQ84_06955) - 1344317..1345126 (-) 810 WP_024703948.1 ABC transporter permease -
  HEQ84_RS06940 (HEQ84_06960) - 1345110..1346066 (-) 957 WP_024703949.1 glycosyltransferase family 2 protein -
  HEQ84_RS06945 (HEQ84_06965) - 1346063..1347211 (-) 1149 WP_024703950.1 glycosyltransferase family 1 protein -
  HEQ84_RS06950 (HEQ84_06970) - 1347318..1348859 (-) 1542 WP_024703951.1 DUF2142 domain-containing protein -
  HEQ84_RS06955 (HEQ84_06975) - 1348866..1349876 (-) 1011 WP_024703952.1 glycosyltransferase -
  HEQ84_RS06960 (HEQ84_06980) - 1349876..1351150 (-) 1275 WP_024703953.1 polysaccharide biosynthesis protein -
  HEQ84_RS06965 (HEQ84_06985) - 1351143..1351475 (-) 333 WP_011226332.1 DUF2304 domain-containing protein -
  HEQ84_RS06970 (HEQ84_06990) - 1351481..1352176 (-) 696 WP_024703954.1 glycosyltransferase family 2 protein -
  HEQ84_RS06975 (HEQ84_06995) rfbD 1352253..1353104 (-) 852 WP_014621820.1 dTDP-4-dehydrorhamnose reductase -
  HEQ84_RS06980 (HEQ84_07000) - 1353181..1354515 (-) 1335 WP_024703955.1 DUF6056 family protein -
  HEQ84_RS06985 (HEQ84_07005) - 1354628..1355554 (-) 927 WP_024703956.1 glycosyltransferase family 2 protein -
  HEQ84_RS06990 (HEQ84_07010) - 1355564..1355899 (-) 336 WP_024703957.1 metal-sulfur cluster assembly factor -
  HEQ84_RS06995 (HEQ84_07015) rpoD 1355953..1357062 (-) 1110 WP_011227440.1 RNA polymerase sigma factor RpoD -
  HEQ84_RS07000 (HEQ84_07020) dnaG 1357066..1358877 (-) 1812 WP_024703958.1 DNA primase -
  HEQ84_RS07005 (HEQ84_07025) mscL 1359017..1359100 (+) 84 Protein_1336 large conductance mechanosensitive channel protein MscL -
  HEQ84_RS07010 (HEQ84_07030) rpsU 1359260..1359436 (-) 177 WP_011681449.1 30S ribosomal protein S21 -
  HEQ84_RS07015 (HEQ84_07035) - 1359630..1360424 (-) 795 WP_023909836.1 ABC transporter substrate-binding protein -
  HEQ84_RS07020 (HEQ84_07040) - 1360486..1361595 (-) 1110 WP_024703959.1 aminotransferase -
  HEQ84_RS07025 (HEQ84_07045) - 1361943..1362740 (-) 798 WP_014621828.1 transporter substrate-binding domain-containing protein -
  HEQ84_RS07030 (HEQ84_07050) - 1362737..1363567 (-) 831 WP_014621829.1 transporter substrate-binding domain-containing protein -
  HEQ84_RS07035 (HEQ84_07055) - 1363781..1364245 (-) 465 WP_011681454.1 8-oxo-dGTP diphosphatase -
  HEQ84_RS07040 (HEQ84_07060) uvrB 1364290..1366281 (-) 1992 WP_014608579.1 excinuclease ABC subunit UvrB -
  HEQ84_RS07045 (HEQ84_07065) - 1366428..1366895 (-) 468 WP_014608580.1 hypothetical protein -
  HEQ84_RS07050 (HEQ84_07070) - 1366968..1367904 (-) 937 Protein_1345 type II CAAX endopeptidase family protein -
  HEQ84_RS07055 (HEQ84_07075) - 1368103..1370313 (+) 2211 WP_014727645.1 ABC transporter substrate-binding protein/permease -
  HEQ84_RS07060 (HEQ84_07080) - 1370313..1371053 (+) 741 WP_024703961.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 497 a.a.        Molecular weight: 55635.50 Da        Isoelectric Point: 10.0972

>NTDB_id=435377 HEQ84_RS06815 WP_011681416.1 1318591..1320084(-) (amiC) [Streptococcus thermophilus strain CS6]
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAVYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAGQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTLFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK

Nucleotide


Download         Length: 1494 bp        

>NTDB_id=435377 HEQ84_RS06815 WP_011681416.1 1318591..1320084(-) (amiC) [Streptococcus thermophilus strain CS6]
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCGAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGCTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTGTCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAATTTTGTGAAGATGAATCTTGGAACTTCATACCCAACTTATGCTGGGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACACTCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA

Domains

Predicted by InterproScan.

Binding-protein-dependent transport system inner membrane component (BPD_transp_1)

(297-490)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiC Streptococcus thermophilus LMD-9

100

100

1
  amiC Streptococcus thermophilus LMG 18311

99.195

100

0.992
  amiC Streptococcus salivarius strain HSISS4

96.982

100

0.97