Detailed information NTG0434857

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: IMP99_RS03745
• Genome accession: NZ_CP062855
• Coordinates: 770229..770888 (-)
• Length: 219 a.a.
• NCBI ID: WP_001221491.1
• Uniprot ID: -
• Organism: Escherichia coli O20:H12 strain Res13-Lact-PEB17-18
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 765229..775888

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IMP99_RS03720 (IMP99_03720)	-	765433..766185 (-)	753	WP_000619462.1	GntR family transcriptional regulator	-
IMP99_RS03725 (IMP99_03725)	-	766472..767803 (+)	1332	WP_000778883.1	MFS transporter	-
IMP99_RS03730 (IMP99_03730)	ygiN	767847..768161 (-)	315	WP_000958598.1	putative quinol monooxygenase	-
IMP99_RS03735 (IMP99_03735)	mdaB	768192..768773 (-)	582	WP_000065430.1	NADPH:quinone oxidoreductase MdaB	-
IMP99_RS03740 (IMP99_03740)	qseC	768883..770232 (-)	1350	WP_000673406.1	quorum sensing histidine kinase QseC	-
IMP99_RS03745 (IMP99_03745)	ciaR	770229..770888 (-)	660	WP_001221491.1	quorum sensing response regulator transcription factor QseB	Regulator
IMP99_RS03750 (IMP99_03750)	ygiW	771040..771432 (+)	393	WP_000712658.1	OB fold stress tolerance protein YgiW	-
IMP99_RS03755 (IMP99_03755)	ygiV	771485..771967 (+)	483	WP_000183494.1	GyrI-like domain-containing protein	-
IMP99_RS03760 (IMP99_03760)	mqsR	772172..772468 (+)	297	WP_000415584.1	type II toxin-antitoxin system toxin MqsR	-
IMP99_RS03765 (IMP99_03765)	mqsA	772470..772865 (+)	396	WP_000650107.1	type II toxin-antitoxin system antitoxin MqsA	-
IMP99_RS03770 (IMP99_03770)	ygiS	772998..774605 (+)	1608	WP_001324265.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24745.66 Da
• Isoelectric Point: 6.6540

>NTDB_id=434857 IMP99_RS03745 WP_001221491.1 770229..770888(-) (ciaR) [Escherichia coli O20:H12 strain Res13-Lact-PEB17-18]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPDKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide

• Length: 660 bp

>NTDB_id=434857 IMP99_RS03745 WP_001221491.1 770229..770888(-) (ciaR) [Escherichia coli O20:H12 strain Res13-Lact-PEB17-18]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGACAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-216)

• Response regulator receiver domain (Response_reg) (3-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.326	100	0.397
ciaR	Streptococcus pneumoniae D39	38.326	100	0.397
ciaR	Streptococcus pneumoniae R6	38.326	100	0.397
ciaR	Streptococcus pneumoniae TIGR4	38.326	100	0.397
ciaR	Streptococcus mutans UA159	35.874	100	0.365
micA	Streptococcus pneumoniae Cp1015	34.498	100	0.361