Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ILQ37_RS11145 Genome accession   NZ_CP062761
Coordinates   2223171..2223827 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O157:H7 strain Z887     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2218171..2228827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ILQ37_RS11115 (ILQ37_11120) dcyD 2219050..2220036 (+) 987 WP_001128225.1 D-cysteine desulfhydrase -
  ILQ37_RS11120 (ILQ37_11125) tcyL 2220051..2220719 (+) 669 WP_001158226.1 cystine ABC transporter permease -
  ILQ37_RS11125 (ILQ37_11130) tcyN 2220716..2221468 (+) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ILQ37_RS11130 (ILQ37_11135) sdiA 2221698..2222420 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  ILQ37_RS11135 (ILQ37_11140) yecF 2222488..2222712 (-) 225 WP_000106479.1 DUF2594 family protein YecF -
  ILQ37_RS11140 (ILQ37_11145) yecU 2222699..2222875 (-) 177 WP_001302050.1 protein YecU -
  ILQ37_RS28500 - 2222913..2223029 (-) 117 WP_001302039.1 hypothetical protein -
  ILQ37_RS11145 (ILQ37_11150) letA 2223171..2223827 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ILQ37_RS11150 (ILQ37_11155) uvrC 2223824..2225656 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ILQ37_RS11155 (ILQ37_11160) pgsA 2225713..2226261 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ILQ37_RS11175 (ILQ37_11180) yecA 2226910..2227575 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=433527 ILQ37_RS11145 WP_000611328.1 2223171..2223827(+) (letA) [Escherichia coli O157:H7 strain Z887]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=433527 ILQ37_RS11145 WP_000611328.1 2223171..2223827(+) (letA) [Escherichia coli O157:H7 strain Z887]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482