Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   HB747_RS25225 Genome accession   NZ_CP050322
Coordinates   5434449..5435786 (+) Length   445 a.a.
NCBI ID   WP_058177112.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain DVT729     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5429449..5440786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB747_RS25200 (HB747_25245) pgeF 5429592..5430320 (-) 729 WP_004352764.1 peptidoglycan editing factor PgeF -
  HB747_RS25205 (HB747_25250) rluD 5430317..5431279 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  HB747_RS25210 (HB747_25255) - 5431425..5432450 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  HB747_RS25215 (HB747_25260) - 5432607..5432852 (+) 246 WP_003102591.1 PP0621 family protein -
  HB747_RS25220 (HB747_25265) pilS 5432842..5434434 (+) 1593 WP_003110428.1 two-component system sensor histidine kinase PilS Regulator
  HB747_RS25225 (HB747_25270) pilR 5434449..5435786 (+) 1338 WP_058177112.1 two-component system response regulator PilR Regulator
  HB747_RS25230 (HB747_25275) thiO 5435832..5436926 (-) 1095 WP_023114840.1 glycine oxidase ThiO -
  HB747_RS25235 (HB747_25280) - 5437061..5437570 (+) 510 WP_017002065.1 Tfp pilus assembly protein FimT/FimU -
  HB747_RS25240 (HB747_25285) - 5437676..5438182 (+) 507 WP_003102598.1 Tfp pilus assembly protein FimT/FimU -
  HB747_RS25245 (HB747_25290) pilV 5438173..5438730 (+) 558 WP_003094697.1 type 4a pilus minor pilin PilV Machinery gene
  HB747_RS25250 (HB747_25295) pilW 5438727..5439551 (+) 825 WP_023114841.1 type 4a pilus minor pilin PilW -
  HB747_RS25255 (HB747_25300) pilX 5439548..5440135 (+) 588 WP_023114842.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49795.10 Da        Isoelectric Point: 5.6424

>NTDB_id=431450 HB747_RS25225 WP_058177112.1 5434449..5435786(+) (pilR) [Pseudomonas aeruginosa strain DVT729]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQDLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=431450 HB747_RS25225 WP_058177112.1 5434449..5435786(+) (pilR) [Pseudomonas aeruginosa strain DVT729]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGACCTGTTCCAGGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.775

100

0.998
  pilR Acinetobacter baumannii strain A118

50.98

100

0.526
  luxO Vibrio cholerae strain A1552

37.946

100

0.382