Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   HB750_RS02525 Genome accession   NZ_CP050273
Coordinates   485183..485890 (+) Length   235 a.a.
NCBI ID   WP_002262930.1    Uniprot ID   -
Organism   Streptococcus mutans strain P1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 480183..490890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB750_RS02495 (HB750_02495) - 480673..480861 (+) 189 WP_002264826.1 DNA-directed RNA polymerase subunit beta -
  HB750_RS02500 (HB750_02500) endA 480903..481784 (+) 882 WP_002264825.1 DNA/RNA non-specific endonuclease Machinery gene
  HB750_RS02505 (HB750_02505) - 481852..482502 (-) 651 WP_002262934.1 amino acid ABC transporter permease -
  HB750_RS02510 (HB750_02510) - 482517..483221 (-) 705 WP_002266143.1 amino acid ABC transporter permease -
  HB750_RS02515 (HB750_02515) - 483239..484051 (-) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  HB750_RS02520 (HB750_02520) - 484048..484830 (-) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  HB750_RS02525 (HB750_02525) vicR 485183..485890 (+) 708 WP_002262930.1 response regulator YycF Regulator
  HB750_RS02530 (HB750_02530) vicK 485883..487235 (+) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HB750_RS02535 (HB750_02535) vicX 487232..488035 (+) 804 WP_019804853.1 MBL fold metallo-hydrolase Regulator
  HB750_RS02540 (HB750_02540) rnc 488142..488837 (+) 696 WP_002266141.1 ribonuclease III -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26914.70 Da        Isoelectric Point: 4.8288

>NTDB_id=431256 HB750_RS02525 WP_002262930.1 485183..485890(+) (vicR) [Streptococcus mutans strain P1]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=431256 HB750_RS02525 WP_002262930.1 485183..485890(+) (vicR) [Streptococcus mutans strain P1]
ATGAAGAAAATTCTAATCGTTGACGATGAAAAACCAATTTCTGATATCATCAAGTTTAACTTGGCTAAGGAAGGTTATGA
CACGATTACAGCCTTTGATGGGCGTGAAGCATTAAGTAAATATGAAGAAGAAAATCCTGACTTGATTATATTGGACTTAA
TGTTACCAGAACTAGACGGTCTTGAAGTGGCTAAGGAAGTTAGAAAAAACAGCCATGTTCCAATTATTATGTTATCAGCT
AAAGACAGTGAGTTTGATAAGGTTATTGGTCTTGAAATTGGTGCTGATGATTATGTGACTAAACCTTTTTCTAATCGTGA
ATTACTGGCGCGTGTAAAAGCGCATCTTCGCCGTACTGAAAATATTGAATCCGCAGTGGCTGAGGAAAATGCTTCAGGTA
TACCTGAAATTATTATTGGGGACTTGCAAATCTTACCAGATGCTTTTGTTGCTAAAAAACGTGGAACAGAGGTAGAGTTA
ACTCACCGTGAGTTTGAGCTGTTGCATCACTTAGCGACACACACAGGTCAGGTGATGACGCGTGAACATTTACTTGAAAC
GGTTTGGGGCTATGATTATTTTGGAGATGTCCGTACTGTTGATGTCACTGTTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCAGAGTACATTTTGACGCGACGCGGTGTTGGTTATTACATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.887

98.298

0.451