Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   HB752_RS04115 Genome accession   NZ_CP050271
Coordinates   811209..812516 (+) Length   435 a.a.
NCBI ID   WP_002264510.1    Uniprot ID   -
Organism   Streptococcus mutans strain S1     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 806209..817516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB752_RS04095 (HB752_04095) phoU 806587..807240 (+) 654 WP_002262211.1 phosphate signaling complex protein PhoU -
  HB752_RS04100 (HB752_04100) - 807281..809830 (+) 2550 WP_002268743.1 M1 family metallopeptidase -
  HB752_RS04105 (HB752_04105) ciaX 810231..810494 (+) 264 WP_002262213.1 three-component system regulator CiaX -
  HB752_RS04110 (HB752_04110) ciaR 810545..811219 (+) 675 WP_002264509.1 three-component system response regulator CiaR Regulator
  HB752_RS04115 (HB752_04115) ciaH 811209..812516 (+) 1308 WP_002264510.1 three-component system sensor histidine kinase CiaH Regulator
  HB752_RS04120 (HB752_04120) rpsT 812605..812859 (-) 255 WP_011074586.1 30S ribosomal protein S20 -
  HB752_RS04125 (HB752_04125) coaA 812913..813833 (-) 921 WP_019804785.1 type I pantothenate kinase -
  HB752_RS04130 (HB752_04130) - 813929..814525 (+) 597 WP_002270201.1 class I SAM-dependent methyltransferase -
  HB752_RS04135 (HB752_04135) - 814634..815911 (+) 1278 WP_019804784.1 pyrimidine-nucleoside phosphorylase -
  HB752_RS04140 (HB752_04140) deoC 815930..816592 (+) 663 WP_002262220.1 deoxyribose-phosphate aldolase -
  HB752_RS04145 (HB752_04145) - 816582..816968 (+) 387 WP_002262221.1 cytidine deaminase -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 49856.29 Da        Isoelectric Point: 9.7262

>NTDB_id=431120 HB752_RS04115 WP_002264510.1 811209..812516(+) (ciaH) [Streptococcus mutans strain S1]
MLIKLRKQKQDENISFFSHFFAVFTGIFFVMTVIIIQVMHFGIYSSVDNSLKIATENVNDYVNMTLSHNNPITEAENGDA
SFKVKSNGQMAANTDTILYDKKHNVINNVNAFSSLYHIRPKLKDIGDIVEQEAKNIYGQTEKYRTVTVKVNNDFYPQIKF
ATIVINTTQLEEANTRYVTIIISVMIVFWLISVIASVYLAKWSQKPILENYEKQKSFVENASHELRTPLAVLQNRLESLF
RKPEATILDSSESIASSLEEVRNMRMLTANLLNLARRDDGIKPEITEIQPRFFDDTFKNYEMIARENGKKLHITNKVNRQ
IKTDKTLLKQLMTILFDNAVKYTDNDGEIWLDVKTTDRSLIFSVADNGQGISDEDKKKIFDRFYRVDKARTRQKGGFGLG
LSLAKQITDSLKGSIIVKDKKPQGVMFEARLLANK

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=431120 HB752_RS04115 WP_002264510.1 811209..812516(+) (ciaH) [Streptococcus mutans strain S1]
ATGCTAATTAAATTAAGAAAACAAAAGCAGGATGAGAATATTTCATTTTTCAGTCATTTCTTTGCTGTTTTTACCGGAAT
ATTCTTTGTTATGACAGTTATTATTATTCAGGTTATGCATTTTGGTATCTATTCTTCAGTTGATAATAGTCTAAAAATAG
CAACTGAGAATGTCAATGATTATGTCAATATGACTCTATCGCATAATAATCCTATTACTGAAGCTGAAAATGGAGATGCC
TCTTTTAAAGTAAAATCAAATGGCCAGATGGCTGCTAATACAGATACTATTCTTTATGATAAAAAGCATAACGTCATCAA
TAATGTCAATGCCTTCTCTTCTTTGTATCATATTCGCCCTAAACTAAAAGATATTGGTGATATTGTTGAACAAGAAGCTA
AGAATATTTACGGTCAGACCGAAAAGTATCGGACAGTGACAGTTAAGGTAAATAATGATTTTTACCCACAGATAAAATTT
GCAACAATTGTTATTAATACAACACAGCTTGAAGAGGCTAATACGCGTTATGTTACGATTATTATCAGTGTGATGATTGT
TTTTTGGCTTATATCAGTTATTGCCAGTGTTTATTTAGCGAAGTGGAGTCAAAAACCGATTCTGGAAAATTATGAAAAGC
AAAAATCATTTGTTGAAAATGCCAGTCATGAATTACGTACTCCCTTGGCTGTTTTGCAAAATCGCTTGGAGAGTTTGTTT
CGAAAACCAGAGGCTACTATCTTAGATTCTTCGGAATCTATTGCTTCTAGTTTGGAAGAGGTCAGAAACATGAGAATGCT
GACAGCAAATCTCCTTAATTTAGCCCGTCGGGATGATGGTATCAAACCAGAAATAACAGAAATTCAACCTCGTTTTTTTG
ATGATACTTTTAAAAATTATGAGATGATCGCTCGAGAAAATGGGAAAAAATTGCATATTACCAATAAGGTCAACCGTCAA
ATTAAGACAGATAAGACTTTGCTGAAGCAATTAATGACTATTCTTTTTGATAATGCTGTCAAATATACAGATAACGACGG
GGAAATTTGGCTGGACGTCAAGACAACTGATCGCAGTTTAATTTTTTCAGTTGCGGACAATGGTCAAGGTATTTCAGACG
AGGATAAGAAGAAAATTTTTGATCGTTTTTATCGCGTCGATAAAGCCAGAACACGACAAAAGGGTGGGTTCGGACTTGGT
TTGTCTTTGGCAAAACAAATAACAGACAGCTTAAAAGGCAGCATTATTGTTAAAGATAAAAAACCACAAGGAGTAATGTT
TGAAGCTCGCCTGCTTGCTAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(215-280)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

99.77

100

0.998
  ciaH Streptococcus pneumoniae Rx1

55.632

100

0.556
  ciaH Streptococcus pneumoniae D39

55.632

100

0.556
  ciaH Streptococcus pneumoniae R6

55.632

100

0.556
  ciaH Streptococcus pneumoniae TIGR4

55.632

100

0.556