Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   HA248_RS00110 Genome accession   NZ_CP050175
Coordinates   21479..21715 (+) Length   78 a.a.
NCBI ID   WP_000939548.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701590     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 16479..26715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA248_RS00100 (HA248_00100) - 20261..20470 (+) 210 Protein_14 transposase -
  HA248_RS00105 (HA248_00105) - 20505..21219 (-) 715 Protein_15 transposase -
  HA248_RS00110 (HA248_00110) comW 21479..21715 (+) 237 WP_000939548.1 sigma(X)-activator ComW Regulator
  HA248_RS00115 (HA248_00115) - 21946..23232 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  HA248_RS00120 (HA248_00120) tadA 23433..23900 (+) 468 WP_000291874.1 tRNA adenosine(34) deaminase TadA -
  HA248_RS00130 (HA248_00130) - 24087..24530 (+) 444 WP_000701992.1 dUTP diphosphatase -
  HA248_RS00135 (HA248_00135) - 24532..25047 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  HA248_RS00140 (HA248_00140) radA 25061..26422 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9716.17 Da        Isoelectric Point: 6.7051

>NTDB_id=430513 HA248_RS00110 WP_000939548.1 21479..21715(+) (comW) [Streptococcus pneumoniae strain PZ900701590]
MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=430513 HA248_RS00110 WP_000939548.1 21479..21715(+) (comW) [Streptococcus pneumoniae strain PZ900701590]
ATGTTACAAAAAATTTATGAGCAGATGACTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974
  comW Streptococcus pneumoniae D39

97.436

100

0.974
  comW Streptococcus pneumoniae R6

97.436

100

0.974
  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756