Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   HBA50_RS04945 Genome accession   NZ_CP050133
Coordinates   1005964..1007343 (+) Length   459 a.a.
NCBI ID   WP_045497282.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1000964..1012343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS04925 (HBA50_04925) csx19 1002057..1002602 (+) 546 WP_045497272.1 CRISPR-associated protein Csx19 -
  HBA50_RS04930 (HBA50_04930) - 1002592..1004388 (+) 1797 WP_166492634.1 RAMP superfamily CRISPR-associated protein -
  HBA50_RS04935 (HBA50_04935) - 1004742..1005179 (+) 438 WP_045497276.1 hypothetical protein -
  HBA50_RS04940 (HBA50_04940) ciaR 1005300..1005974 (+) 675 WP_045497279.1 response regulator transcription factor Regulator
  HBA50_RS04945 (HBA50_04945) ciaH 1005964..1007343 (+) 1380 WP_045497282.1 sensor histidine kinase KdpD Regulator
  HBA50_RS04950 (HBA50_04950) - 1007418..1007804 (+) 387 WP_005590267.1 VOC family protein -
  HBA50_RS04955 (HBA50_04955) - 1007894..1009291 (+) 1398 WP_045497284.1 polysaccharide deacetylase family protein -
  HBA50_RS04960 (HBA50_04960) - 1009374..1010462 (-) 1089 WP_306452456.1 DEAD/DEAH box helicase -
  HBA50_RS04965 (HBA50_04965) - 1010455..1011435 (-) 981 WP_045497289.1 Gfo/Idh/MocA family protein -
  HBA50_RS04970 (HBA50_04970) udk 1011540..1012175 (+) 636 WP_005591973.1 uridine kinase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 52272.73 Da        Isoelectric Point: 8.7572

>NTDB_id=430216 HBA50_RS04945 WP_045497282.1 1005964..1007343(+) (ciaH) [Streptococcus cristatus ATCC 51100]
MLNKLKKALYADDFSYFIRYFGVFTLIFSAMTLIIIQVMRSSLYTTVDDNLKSLSQNPAWVANLAYRTTGRQYQEPENKD
SEHKDSESVQAHDIKIEEPGRVNVSANTSAILLNDDYQNVSAKNSFLNFDAIKFNKRFLNQIKQIQLTNSYGQVESYRAY
MFDIDPDDEIENVKYAVVMTSISQLEQTSEKHEKLIAIVMISFWGISLIASIYLARMSVKPLLDSMQKQKSFVENASHEL
RTPLAVLQNRLESLFRKPEATIMESSESIASSLEEVRNMRLLTTNLLNLARRDDGIKPEYGEVTPDFFTTAFSNYAIIAE
ESDKVFDFKNLVSKSITTDKVLLKQVMTILFDNAIKYTEEDGEIYFVASANDRILTLRISDNGPGIAGDDKKKVFDRFYR
VDKARTRQKGGFGLGLSLAKQIVDALKGTITVKDNKPRGTIFEIKVPLRSDIRKRISKS

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=430216 HBA50_RS04945 WP_045497282.1 1005964..1007343(+) (ciaH) [Streptococcus cristatus ATCC 51100]
ATGCTGAATAAACTCAAAAAAGCCTTATATGCGGATGATTTTTCTTATTTCATTCGCTATTTTGGTGTATTCACCCTGAT
TTTCTCGGCCATGACGCTCATTATTATCCAAGTCATGCGCTCTAGCCTCTACACGACCGTTGATGATAATCTCAAAAGTC
TCAGTCAAAATCCCGCCTGGGTAGCCAATCTAGCCTATCGGACGACGGGGCGGCAATACCAAGAGCCAGAGAACAAGGAT
TCAGAGCACAAAGATTCAGAGTCTGTGCAAGCTCATGATATCAAGATTGAGGAACCGGGCAGGGTCAATGTCAGTGCCAA
TACCTCAGCCATTCTTTTGAATGATGATTATCAGAATGTATCTGCAAAAAATAGCTTTTTGAACTTTGATGCGATTAAAT
TTAATAAACGATTTCTTAATCAAATCAAGCAAATTCAGCTGACCAATAGCTATGGACAGGTCGAGAGTTATCGGGCCTAT
ATGTTCGACATTGATCCAGATGATGAAATTGAAAATGTCAAATACGCAGTTGTCATGACCAGTATCAGCCAGCTGGAGCA
GACTAGCGAAAAGCATGAAAAGCTGATTGCCATTGTCATGATTAGCTTCTGGGGTATTTCTTTGATTGCTAGTATCTATC
TGGCGCGGATGAGTGTCAAGCCTCTCTTGGACAGCATGCAAAAGCAGAAGTCTTTTGTTGAAAATGCCAGCCACGAATTG
CGGACGCCTCTGGCCGTGCTGCAAAATCGTCTGGAGTCTCTCTTCCGTAAGCCTGAGGCCACGATTATGGAGTCTAGTGA
GAGTATCGCATCTAGTTTAGAGGAAGTGCGAAATATGCGCCTATTGACGACCAATTTACTCAACCTAGCTCGGCGCGATG
ACGGTATCAAGCCAGAATACGGTGAAGTCACACCAGACTTCTTCACAACAGCTTTTTCTAACTATGCTATTATTGCGGAG
GAAAGCGATAAGGTCTTTGATTTCAAAAATCTGGTTTCAAAATCAATCACGACAGACAAAGTCTTGCTCAAGCAGGTAAT
GACCATCCTTTTTGATAATGCCATCAAATACACAGAGGAGGATGGAGAGATCTATTTCGTGGCCTCCGCCAATGATCGGA
TCTTGACCTTGCGTATTTCTGACAATGGTCCAGGGATTGCGGGCGACGACAAGAAAAAAGTCTTCGATCGTTTTTATCGG
GTGGATAAGGCTCGGACTCGTCAAAAAGGTGGATTTGGACTAGGACTTTCCTTGGCGAAACAAATCGTGGACGCCTTAAA
AGGAACCATCACAGTCAAAGATAACAAACCGCGTGGAACCATTTTTGAAATCAAAGTTCCCCTTAGGTCAGATATTAGAA
AACGAATTAGCAAAAGCTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(230-295)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(339-449)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

64.114

99.564

0.638
  ciaH Streptococcus pneumoniae D39

64.114

99.564

0.638
  ciaH Streptococcus pneumoniae R6

64.114

99.564

0.638
  ciaH Streptococcus pneumoniae TIGR4

64.114

99.564

0.638
  ciaH Streptococcus mutans UA159

51.794

97.168

0.503