Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   HBA50_RS02675 Genome accession   NZ_CP050133
Coordinates   524722..526023 (+) Length   433 a.a.
NCBI ID   WP_045500910.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 519722..531023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS02650 (HBA50_02650) - 520504..521136 (+) 633 WP_045500904.1 response regulator transcription factor -
  HBA50_RS02655 (HBA50_02655) - 521174..522574 (+) 1401 WP_045500955.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  HBA50_RS02660 (HBA50_02660) - 522574..522936 (+) 363 WP_005591890.1 S1 RNA-binding domain-containing protein -
  HBA50_RS02665 (HBA50_02665) cysK 522984..523913 (-) 930 WP_045500906.1 cysteine synthase A -
  HBA50_RS02670 (HBA50_02670) - 524030..524665 (-) 636 WP_045500908.1 YigZ family protein -
  HBA50_RS02675 (HBA50_02675) comFA/cflA 524722..526023 (+) 1302 WP_045500910.1 DEAD/DEAH box helicase Machinery gene
  HBA50_RS02680 (HBA50_02680) comFC/cflB 526020..526685 (+) 666 WP_045500912.1 ComF family protein Machinery gene
  HBA50_RS02685 (HBA50_02685) raiA 526767..527309 (+) 543 WP_045500914.1 ribosome-associated translation inhibitor RaiA -
  HBA50_RS02690 (HBA50_02690) - 527459..530572 (+) 3114 WP_045500916.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49795.72 Da        Isoelectric Point: 8.9686

>NTDB_id=430205 HBA50_RS02675 WP_045500910.1 524722..526023(+) (comFA/cflA) [Streptococcus cristatus ATCC 51100]
MLERNDCLGRIFTKDQISPELRLQAQQLPSMREERRKLFCGRCGSQVDKENYQLPVNAYYCRECVILGRVRSDQELYYFP
QEDFPENQVLKWQGQLTAFQAKVSQGLLESVAQKQNSLVHAVTGAGKTEMIYQVIAEVIDRGGAVCLASPRIDVCLELYR
RLKLDFACPISLLHGESEPYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPVLYHAVKQSVKEEETTIFLTATS
TDELDKKVQKGELKRLSLPRRFHGNPLIVPQKVWLADFQKYLSKKKLPPKLKKYIERQRKTGFPLLIFASEIKRGQEFAQ
VLEKIFPAERVGFVASTTENRLEIVEEFRKREITILVTTTILERGVTFPCVDVFVLEANHRLFSRSALVQISGRVGRSME
RPTGDLLFFHDGTTRSIEKAIREIKLMNKEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=430205 HBA50_RS02675 WP_045500910.1 524722..526023(+) (comFA/cflA) [Streptococcus cristatus ATCC 51100]
ATGTTAGAAAGAAATGATTGCCTAGGTAGGATATTTACAAAAGATCAGATCAGTCCCGAACTGCGCTTGCAGGCCCAGCA
GTTACCCAGTATGCGAGAGGAAAGGAGAAAGTTATTTTGCGGCCGCTGTGGCTCTCAAGTAGACAAGGAGAACTACCAGC
TACCTGTCAATGCCTACTATTGTAGGGAATGCGTGATTTTGGGGCGAGTTCGGAGTGATCAAGAACTCTACTATTTTCCG
CAGGAAGATTTTCCAGAAAATCAGGTACTCAAGTGGCAGGGGCAATTAACAGCCTTTCAAGCGAAAGTTTCTCAGGGACT
GTTAGAGTCAGTTGCTCAAAAGCAGAATAGCCTAGTCCATGCAGTGACTGGGGCGGGCAAAACGGAAATGATTTATCAGG
TGATCGCAGAAGTGATTGATCGTGGAGGTGCCGTTTGCCTAGCCAGCCCTCGGATTGATGTCTGTTTGGAGCTTTATCGC
CGGCTCAAGCTGGATTTTGCCTGCCCTATTTCGCTTTTGCATGGAGAATCCGAGCCATATTTTCGCAGTCCCTTGGTCAT
TGCTACCACTCATCAGCTTCTTAAATTTTATCGAGCCTTTGATTTGTTGATCGTGGACGAGGTGGATGCTTTTCCTTATG
TGGACAATCCTGTGCTCTACCATGCCGTGAAGCAGTCGGTCAAGGAGGAGGAAACGACAATTTTCTTAACTGCCACTTCG
ACGGATGAGTTGGATAAAAAAGTCCAAAAAGGAGAACTAAAACGCCTTAGTCTTCCTCGCCGCTTCCATGGCAATCCTTT
GATTGTGCCCCAAAAAGTTTGGCTGGCAGATTTTCAAAAATATCTATCGAAAAAGAAACTACCGCCTAAATTGAAGAAAT
ATATCGAGAGACAGAGAAAAACAGGCTTTCCTTTACTGATCTTTGCCTCGGAAATCAAAAGAGGTCAAGAATTTGCGCAA
GTTTTAGAAAAGATTTTTCCAGCGGAAAGAGTCGGATTTGTGGCTTCAACAACTGAAAATCGTTTAGAAATCGTTGAAGA
GTTTCGCAAGCGAGAAATTACCATTTTGGTTACGACAACCATCTTAGAGCGTGGTGTGACCTTTCCCTGTGTAGATGTTT
TTGTTCTAGAGGCCAACCATCGTCTCTTTAGCCGTAGCGCCTTGGTGCAGATTTCTGGTCGAGTGGGACGTAGCATGGAG
CGACCGACGGGAGATTTACTCTTCTTTCACGACGGCACCACACGTTCAATCGAAAAAGCGATTCGTGAAATCAAGCTGAT
GAACAAGGAGGCCGGCCTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(293-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

72.535

98.383

0.714
  comFA/cflA Streptococcus mitis SK321

71.831

98.383

0.707
  comFA/cflA Streptococcus pneumoniae D39

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae R6

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae TIGR4

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae Rx1

71.495

98.845

0.707
  comFA Lactococcus lactis subsp. cremoris KW2

52.381

96.998

0.508
  comFA Latilactobacillus sakei subsp. sakei 23K

40.698

99.307

0.404
  comFA Bacillus subtilis subsp. subtilis str. 168

39.903

94.919

0.379