Detailed information NTG0422971

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: IF130_RS06095
• Genome accession: NZ_CP061840
• Coordinates: 1335989..1336666 (-)
• Length: 225 a.a.
• NCBI ID: WP_011213604.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pneumophila strain AW-13-4
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1330989..1341666

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF130_RS06070 (IF130_06070)	ruvC	1331160..1331684 (+)	525	WP_011213599.1	crossover junction endodeoxyribonuclease RuvC	-
IF130_RS06075 (IF130_06075)	ruvA	1331681..1332280 (+)	600	WP_011213600.1	Holliday junction branch migration protein RuvA	-
IF130_RS06080 (IF130_06080)	-	1332330..1332650 (+)	321	WP_011213601.1	hypothetical protein	-
IF130_RS06085 (IF130_06085)	lem8	1332691..1334295 (-)	1605	WP_011213602.1	Dot/Icm T4SS effector Lem8	-
IF130_RS06090 (IF130_06090)	-	1334577..1335992 (-)	1416	WP_011213603.1	ATP-binding protein	-
IF130_RS06095 (IF130_06095)	ciaR	1335989..1336666 (-)	678	WP_011213604.1	response regulator	Regulator
IF130_RS06100 (IF130_06100)	-	1336727..1337272 (-)	546	WP_011213605.1	septation protein A	-
IF130_RS06105 (IF130_06105)	-	1337515..1338954 (-)	1440	WP_011213606.1	LysM peptidoglycan-binding domain-containing protein	-
IF130_RS06110 (IF130_06110)	gloB	1339068..1339832 (-)	765	WP_011213607.1	hydroxyacylglutathione hydrolase	-
IF130_RS06115 (IF130_06115)	-	1339836..1340684 (-)	849	WP_011213608.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
IF130_RS06120 (IF130_06120)	-	1340970..1341179 (+)	210	WP_011213609.1	hypothetical protein	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25151.74 Da
• Isoelectric Point: 4.9981

>NTDB_id=422971 IF130_RS06095 WP_011213604.1 1335989..1336666(-) (ciaR) [Legionella pneumophila subsp. pneumophila strain AW-13-4]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide

• Length: 678 bp

>NTDB_id=422971 IF130_RS06095 WP_011213604.1 1335989..1336666(-) (ciaR) [Legionella pneumophila subsp. pneumophila strain AW-13-4]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTACGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTAAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTAGTAAGGCGCTCTCAGGGCAGAGCTGATTCCGTGCTGCAATATAAAAATATTACTC
TCGATCCTGCTGCTCATTCTGTATTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTACAGAAA
TTACTTGAAAACAGTGGCCAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTAGAAGTTCACATCCATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (148-215)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae D39	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae R6	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae TIGR4	38.356	97.333	0.373
ciaR	Streptococcus mutans UA159	37.9	97.333	0.369
micA	Streptococcus pneumoniae Cp1015	35.345	100	0.364