Detailed information NTG0421085

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: D8K17_RS11000
• Genome accession: NZ_CP061322
• Coordinates: 2167118..2167783 (+)
• Length: 221 a.a.
• NCBI ID: WP_004254535.1
• Uniprot ID: Q9CE22
• Organism: Lactococcus lactis subsp. lactis bv. diacetylactis strain S50
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2162118..2172783

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D8K17_RS10970 (D8K17_010990)	-	2163260..2163586 (-)	327	WP_010906269.1	lactococcin 972 family bacteriocin	-
D8K17_RS10975 (D8K17_010995)	-	2163886..2164614 (-)	729	WP_004254546.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
D8K17_RS10980 (D8K17_011000)	-	2164807..2165028 (+)	222	WP_010906270.1	YqgQ family protein	-
D8K17_RS10985 (D8K17_011005)	-	2165062..2166033 (+)	972	WP_004254542.1	ROK family glucokinase	-
D8K17_RS10990 (D8K17_011010)	-	2166036..2166422 (+)	387	WP_010906271.1	rhodanese-like domain-containing protein	-
D8K17_RS10995 (D8K17_011015)	-	2166505..2166951 (-)	447	WP_004254538.1	DNA starvation/stationary phase protection protein	-
D8K17_RS11000 (D8K17_011020)	cclA/cilC	2167118..2167783 (+)	666	WP_004254535.1	A24 family peptidase	Machinery gene
D8K17_RS11005 (D8K17_011025)	dinB	2167734..2168825 (-)	1092	WP_010906272.1	DNA polymerase IV	-
D8K17_RS11010 (D8K17_011030)	-	2168904..2169395 (-)	492	WP_010906273.1	prolyl-tRNA synthetase associated domain-containing protein	-
D8K17_RS11015 (D8K17_011035)	-	2169474..2170967 (-)	1494	WP_010906274.1	basic amino acid/polyamine antiporter	-
D8K17_RS11020 (D8K17_011040)	-	2171159..2172289 (-)	1131	WP_010906275.1	aminotransferase	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 25664.87 Da
• Isoelectric Point: 8.8481

>NTDB_id=421085 D8K17_RS11000 WP_004254535.1 2167118..2167783(+) (cclA/cilC) [Lactococcus lactis subsp. lactis bv. diacetylactis strain S50]
MDILFIFLIGSIFGSFFGLIVDRIPLRKSIIFGRSHCDSCQQLLAYRDLIPIFSQISSGSHCRYCKSKIPYLYVFLEFSS
ALIFVLAWVNYLKPSQFLLIILSLILSAFDYRQHSFPFVIWFIFALSFILIFPLSPLFYFWLILAVLAEKFNLRVGSGDF
LWFFTASFSLTFLNEMLLLQIACSLGIIYYLITKKRVEIAFIPFLTIAYLMLLFGHQILSP

Nucleotide

• Length: 666 bp

>NTDB_id=421085 D8K17_RS11000 WP_004254535.1 2167118..2167783(+) (cclA/cilC) [Lactococcus lactis subsp. lactis bv. diacetylactis strain S50]
ATGGACATTTTATTTATATTTTTAATTGGAAGTATTTTTGGCTCCTTTTTTGGCTTAATAGTTGACCGTATTCCACTAAG
AAAATCAATTATTTTTGGACGCTCACATTGTGATTCTTGTCAGCAACTTTTAGCCTATCGTGATCTAATTCCTATTTTTT
CTCAAATAAGCTCTGGCTCACATTGCCGTTATTGTAAAAGTAAAATTCCATATTTATATGTTTTTTTGGAGTTCTCATCA
GCTTTAATTTTTGTTTTAGCTTGGGTAAATTATCTTAAACCTAGTCAATTTTTACTGATTATTCTTTCACTAATTTTATC
TGCTTTTGATTATCGTCAGCACAGTTTTCCTTTTGTTATCTGGTTTATTTTTGCACTCAGTTTTATTTTAATATTTCCTC
TTTCTCCCCTTTTCTATTTTTGGCTTATTTTAGCCGTCTTAGCTGAAAAATTCAATTTAAGAGTTGGCAGCGGTGATTTT
TTATGGTTTTTTACCGCTTCATTTTCTCTAACTTTCTTAAACGAAATGCTGCTCCTTCAAATCGCTTGTTCACTTGGTAT
CATTTATTATCTAATCACAAAAAAACGAGTTGAAATTGCCTTCATCCCGTTTCTAACTATTGCATATCTAATGTTGCTTT
TTGGGCACCAAATTCTGTCACCGTAA

Domains

Predicted by InterProScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-90)

3D structure

• AlphaFold DB: Q9CE22

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis SK321	37.9	99.095	0.376
cclA/cilC	Streptococcus pneumoniae Rx1	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae D39	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae R6	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae TIGR4	37.674	97.285	0.367