Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   D39N_RS00110 Genome accession   NZ_CP061208
Coordinates   22168..22404 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain D39_P0     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 17168..27404
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D39N_RS00100 - 20225..21071 (+) 847 Protein_14 IS630 family transposase -
  D39N_RS00105 - 21106..21902 (-) 797 Protein_15 transposase -
  D39N_RS00110 (D39N_00024) comW 22168..22404 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  D39N_RS00115 (D39N_00025) - 22635..23921 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  D39N_RS00120 (D39N_00026) tadA 24122..24589 (+) 468 WP_000291874.1 tRNA adenosine(34) deaminase TadA -
  D39N_RS00130 (D39N_00027) - 24776..25219 (+) 444 WP_000701992.1 dUTP diphosphatase -
  D39N_RS00135 (D39N_00028) - 25221..25736 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  D39N_RS00140 (D39N_00029) radA 25750..27111 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=420908 D39N_RS00110 WP_000939545.1 22168..22404(+) (comW) [Streptococcus pneumoniae strain D39_P0]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=420908 D39N_RS00110 WP_000939545.1 22168..22404(+) (comW) [Streptococcus pneumoniae strain D39_P0]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGGTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744