Detailed information NTG0420422

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M654_RS03410
• Genome accession: NZ_CP048273
• Coordinates: 703570..704727 (+)
• Length: 385 a.a.
• NCBI ID: WP_026588948.1
• Uniprot ID: A0A6I7F9U3
• Organism: Bacillus sp. NSP9.1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 698570..709727

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M654_RS03390 (M654_003385)	-	699105..700169 (+)	1065	WP_026588952.1	MraY family glycosyltransferase	-
M654_RS03395 (M654_003390)	-	700215..701558 (-)	1344	WP_081692877.1	kelch-like protein	-
M654_RS03400 (M654_003395)	-	701620..702696 (-)	1077	WP_026588950.1	LCP family protein	-
M654_RS03405 (M654_003400)	-	702710..703348 (-)	639	WP_026588949.1	YigZ family protein	-
M654_RS03410 (M654_003405)	degS	703570..704727 (+)	1158	WP_026588948.1	histidine kinase	Regulator
M654_RS03415 (M654_003410)	degU	704809..705498 (+)	690	WP_026588947.1	two-component system response regulator DegU	Regulator
M654_RS03420 (M654_003415)	-	705618..706460 (+)	843	WP_026588946.1	DegV family protein	-
M654_RS03425 (M654_003420)	comFA	706595..707983 (+)	1389	WP_026588944.1	DEAD/DEAH box helicase	Machinery gene
M654_RS03430 (M654_003425)	-	708040..708324 (+)	285	WP_026588943.1	competence protein ComFB	-
M654_RS03435 (M654_003430)	comFC	708281..709015 (+)	735	WP_035428518.1	ComF family protein	Machinery gene
M654_RS03440 (M654_003435)	-	709074..709493 (+)	420	WP_026588941.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44577.23 Da
• Isoelectric Point: 6.6064

>NTDB_id=420422 M654_RS03410 WP_026588948.1 703570..704727(+) (degS) [Bacillus sp. NSP9.1]
MSVSKMDSKVLDSIIMKMLKTVDGSKDEVFQIGEQSRQQYEGLVEELKQIKQQVNEVIDLGDRLEVHARHARNRLSEVSR
NFHKFSEEEIREAYEKAHKLQVELTMIQQREKQLREKRDDLERRLLGLQEIIERSEGLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVLMRSELIERIFRDKGTDEGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEDYHGKAKIHFQCIGESEDRRIAPRFEVALFRLAQEAVTNALKHSESTEIHVKVEI
TKDFVTLIIKDNGTGFDIKEVKGNKNKSFGLLGMKERVDLLEGSMTIDSKIGLGTFILIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=420422 M654_RS03410 WP_026588948.1 703570..704727(+) (degS) [Bacillus sp. NSP9.1]
GTGAGTGTTTCCAAAATGGACTCCAAAGTCTTAGATTCAATCATTATGAAGATGTTAAAAACGGTTGACGGGAGCAAGGA
CGAAGTCTTTCAAATCGGCGAGCAGTCCCGTCAGCAATACGAAGGCTTAGTGGAAGAGCTGAAGCAGATTAAACAGCAAG
TCAACGAAGTCATCGATCTCGGAGACAGGCTTGAGGTGCATGCGCGCCATGCCCGAAACCGCTTGTCAGAGGTCAGCCGC
AACTTTCATAAATTTAGCGAAGAAGAAATTCGCGAGGCTTATGAAAAAGCGCACAAGCTGCAAGTCGAGCTGACAATGAT
CCAGCAGCGGGAAAAGCAGCTGAGAGAAAAGCGCGATGATTTGGAACGGAGGCTGTTGGGCCTTCAGGAAATCATCGAGC
GCTCTGAAGGGCTTGTCAGCCAAATTACTGTCGTCTTGAACTATTTAAATCAAGATCTGCGCCAGGTGGGCGTCCTTCTG
GAGGATGCGCAGGCCAAACAGGATTTCGGACTGCGGATCATTGAAGCGCAGGAGGAAGAAAGAAAAAGAGTCTCCCGGGA
AATACACGACGGACCGGCGCAAATGCTCGCCAACGTCTTAATGAGATCGGAATTGATCGAGCGCATTTTCAGGGATAAAG
GAACGGATGAAGGCTTCCAGGAAATCAAAAACCTCCGTCAAAACGTCCGCAATGCCCTTTATGAAGTGAGACGGATTATT
TATGATTTAAGGCCGATGGCTTTAGATGATTTAGGATTGATTCCGACGCTCAGAAAATACTTGAATACAATCGAAGATTA
TCATGGAAAAGCGAAAATTCATTTCCAATGCATCGGAGAATCTGAAGACAGGCGAATTGCGCCGCGATTTGAGGTGGCAC
TGTTCCGCCTTGCCCAGGAAGCGGTCACAAATGCCTTAAAACACTCCGAATCAACAGAGATCCATGTTAAAGTAGAAATA
ACAAAAGATTTTGTGACACTGATCATTAAAGACAATGGAACAGGCTTTGATATAAAAGAAGTGAAAGGCAACAAAAACAA
ATCTTTTGGTCTTCTTGGCATGAAAGAGAGAGTCGATTTGCTCGAAGGTTCGATGACAATAGATTCGAAAATAGGTCTCG
GGACATTTATTTTGATCAAAGTTCCGCTTTCTTTGTAA

Domains

Predicted by InterproScan.

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (292-384)

3D structure

• AlphaFold DB: A0A6I7F9U3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	88.831	100	0.888