Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SPPN_RS08740 Genome accession   NC_015875
Coordinates   1703624..1704361 (-) Length   245 a.a.
NCBI ID   WP_001219128.1    Uniprot ID   A0AAQ2VZC5
Organism   Streptococcus pseudopneumoniae IS7493     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1698624..1709361
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS08725 (SPPN_08870) - 1700652..1702013 (+) 1362 WP_001069059.1 bacteriocin secretion accessory protein -
  SPPN_RS08730 (SPPN_08875) blpC 1702070..1702225 (+) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  SPPN_RS08735 (SPPN_08880) - 1702270..1703610 (-) 1341 WP_001028650.1 sensor histidine kinase -
  SPPN_RS08740 (SPPN_08885) comE/blpR 1703624..1704361 (-) 738 WP_001219128.1 response regulator transcription factor Regulator
  SPPN_RS08745 (SPPN_08890) - 1704366..1704704 (-) 339 WP_000682127.1 LytTR family DNA-binding domain-containing protein -
  SPPN_RS08750 (SPPN_08900) - 1705063..1705314 (+) 252 WP_001130045.1 hypothetical protein -
  SPPN_RS08755 (SPPN_08905) - 1705343..1705666 (+) 324 WP_000131861.1 hypothetical protein -
  SPPN_RS08760 (SPPN_08910) - 1705728..1706777 (-) 1050 WP_000653756.1 ABC transporter permease -
  SPPN_RS08765 (SPPN_08915) pptA 1706774..1707505 (-) 732 WP_000889950.1 ABC transporter ATP-binding protein Regulator
  SPPN_RS08770 (SPPN_08920) - 1707573..1707983 (+) 411 WP_001278321.1 HIT family protein -
  SPPN_RS08775 (SPPN_08925) - 1707993..1708280 (+) 288 WP_000777749.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28726.88 Da        Isoelectric Point: 6.4140

>NTDB_id=42015 SPPN_RS08740 WP_001219128.1 1703624..1704361(-) (comE/blpR) [Streptococcus pseudopneumoniae IS7493]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGGHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=42015 SPPN_RS08740 WP_001219128.1 1703624..1704361(-) (comE/blpR) [Streptococcus pseudopneumoniae IS7493]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGGCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTAGAGGTGGCTAGAAAGATTCGGGATCGAGAC
CCCTATGCCCTGATTGTCTTTGTGACGACTCACTCAGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCTTGTCAGCAGAGGAGTTTGAATCTCGGATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTTCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCGCCCAGAGCCCATCGTGTTATTCTTTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTTAAGCAGGAACCCCGTCTCTTGCAGTGCCACCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGTTGTCTGATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.321

99.184

0.539
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment