Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SPPN_RS08400 Genome accession   NC_015875
Coordinates   1642912..1643571 (+) Length   219 a.a.
NCBI ID   WP_000565602.1    Uniprot ID   A0A0T8TFT6
Organism   Streptococcus pseudopneumoniae IS7493     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1637912..1648571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS08380 (SPPN_08495) - 1639232..1640122 (-) 891 WP_000797956.1 carbohydrate ABC transporter permease -
  SPPN_RS08385 (SPPN_08500) - 1640133..1641050 (-) 918 WP_001084980.1 ABC transporter permease -
  SPPN_RS08390 (SPPN_08505) - 1641204..1642205 (-) 1002 WP_000230199.1 LacI family DNA-binding transcriptional regulator -
  SPPN_RS08395 (SPPN_08510) - 1642387..1642842 (-) 456 WP_000586775.1 GNAT family N-acetyltransferase -
  SPPN_RS08400 (SPPN_08515) cclA/cilC 1642912..1643571 (+) 660 WP_000565602.1 prepilin peptidase Machinery gene
  SPPN_RS08405 (SPPN_08520) - 1643623..1644774 (-) 1152 WP_000481761.1 XRE family transcriptional regulator -
  SPPN_RS08410 (SPPN_08525) - 1644789..1645520 (-) 732 WP_000934350.1 hypothetical protein -
  SPPN_RS13615 - 1645644..1645742 (+) 99 Protein_1698 prepilin peptidase -
  SPPN_RS08415 (SPPN_08530) trpA 1645714..1646490 (-) 777 WP_001127013.1 tryptophan synthase subunit alpha -
  SPPN_RS08420 (SPPN_08535) trpB 1646483..1647706 (-) 1224 WP_000331250.1 tryptophan synthase subunit beta -
  SPPN_RS08425 (SPPN_08540) - 1647684..1648283 (-) 600 WP_000169908.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24807.98 Da        Isoelectric Point: 7.5762

>NTDB_id=42013 SPPN_RS08400 WP_000565602.1 1642912..1643571(+) (cclA/cilC) [Streptococcus pseudopneumoniae IS7493]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISPASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMISFLILGILAHFIDIRMGAGDFL
FLASCALVFSATELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=42013 SPPN_RS08400 WP_000565602.1 1642912..1643571(+) (cclA/cilC) [Streptococcus pseudopneumoniae IS7493]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGTATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTCCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGATCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGCAACAGAATTGCTCATCTTGATTCAGTTTGCTTCTGCAACGGGGATTCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTCGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8TFT6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

98.174

100

0.982
  cclA/cilC Streptococcus pneumoniae D39

98.174

100

0.982
  cclA/cilC Streptococcus pneumoniae R6

98.174

100

0.982
  cclA/cilC Streptococcus mitis SK321

93.607

100

0.936
  cclA/cilC Streptococcus pneumoniae TIGR4

93.151

100

0.932
  cclA/cilC Streptococcus mitis NCTC 12261

88.128

100

0.881

Multiple sequence alignment