Detailed information
Bioinformatically predicted
Overview
| Name | ciaH | Type | Regulator |
| Locus tag | SPPN_RS04035 | Genome accession | NC_015875 |
| Coordinates | 776083..777417 (+) | Length | 444 a.a. |
| NCBI ID | WP_000491804.1 | Uniprot ID | - |
| Organism | Streptococcus pseudopneumoniae IS7493 | ||
| Function | repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation |
||
Genomic Context
Location: 771083..782417
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SPPN_RS04015 (SPPN_04075) | - | 771357..772226 (+) | 870 | WP_001245827.1 | putative PEP-binding protein | - |
| SPPN_RS04020 (SPPN_04080) | - | 772201..772641 (+) | 441 | WP_000188832.1 | ASCH domain-containing protein | - |
| SPPN_RS04025 (SPPN_04085) | - | 772764..775310 (+) | 2547 | WP_001149128.1 | M1 family metallopeptidase | - |
| SPPN_RS04030 (SPPN_04090) | ciaR | 775419..776093 (+) | 675 | WP_000590626.1 | two-component system response regulator CiaR | Regulator |
| SPPN_RS04035 (SPPN_04095) | ciaH | 776083..777417 (+) | 1335 | WP_000491804.1 | two-component system sensor histidine kinase CiaH | Regulator |
| SPPN_RS04040 (SPPN_04100) | - | 777587..777874 (-) | 288 | WP_001111517.1 | DUF3270 domain-containing protein | - |
| SPPN_RS04045 (SPPN_04105) | - | 778014..778943 (+) | 930 | WP_014017228.1 | peptidase U32 family protein | - |
| SPPN_RS04050 (SPPN_04110) | - | 779142..781592 (+) | 2451 | WP_000848728.1 | bifunctional DnaQ family exonuclease/ATP-dependent helicase | - |
Sequence
Protein
Download Length: 444 a.a. Molecular weight: 50822.60 Da Isoelectric Point: 8.8761
>NTDB_id=41992 SPPN_RS04035 WP_000491804.1 776083..777417(+) (ciaH) [Streptococcus pseudopneumoniae IS7493]
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDKLHVLSENPQAVIQLAVNRATEEIKDLENAR
ADASKVEIKPNVSSNTEVILFDKDFTQLLSGNRFLGLDKIRLEKKELGHIYQIQVFNSYGQEEIYRMILMETNISSVSTN
IKYAAVLINTSQLEQASQKHEQLIVVVMVSFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMDVSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENDRVFRFENRI
HRPIVTDQLLLKQLMTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGVGISTEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGTITVKDNKPKGTIFEVKIAIHTPSKKKK
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDKLHVLSENPQAVIQLAVNRATEEIKDLENAR
ADASKVEIKPNVSSNTEVILFDKDFTQLLSGNRFLGLDKIRLEKKELGHIYQIQVFNSYGQEEIYRMILMETNISSVSTN
IKYAAVLINTSQLEQASQKHEQLIVVVMVSFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMDVSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENDRVFRFENRI
HRPIVTDQLLLKQLMTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGVGISTEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGTITVKDNKPKGTIFEVKIAIHTPSKKKK
Nucleotide
Download Length: 1335 bp
>NTDB_id=41992 SPPN_RS04035 WP_000491804.1 776083..777417(+) (ciaH) [Streptococcus pseudopneumoniae IS7493]
ATGTTCAGTAAACTAAAAAAAACATGGTATGCGGATGATTTTAGTTATTTTATCCGCAACTTTGGTGTCTTCACTCTGAT
TTTCTCTACCATGACTCTGATTATTTTACAGGTCATGCACTCGAGTCTCTATACTTCAGTGGATGATAAGCTCCACGTAC
TAAGTGAAAATCCTCAAGCAGTTATTCAACTGGCAGTGAATAGGGCAACAGAAGAGATTAAAGATTTAGAAAATGCTAGG
GCGGACGCTAGTAAAGTAGAAATAAAACCTAATGTCAGTTCCAATACGGAAGTCATTCTCTTTGATAAGGACTTTACTCA
ACTTCTTTCTGGAAATCGATTTTTGGGCTTGGATAAGATTAGGTTAGAGAAAAAAGAACTAGGCCATATCTACCAGATTC
AGGTTTTTAATAGCTATGGGCAGGAAGAAATCTATCGCATGATTTTGATGGAAACCAATATCAGTTCGGTTTCAACCAAT
ATCAAGTATGCTGCTGTCTTGATAAATACCAGTCAGTTGGAGCAGGCCAGTCAAAAGCATGAGCAATTGATTGTCGTTGT
GATGGTAAGTTTCTGGATTTTGTCTTTGCTTGCAAGTCTTTATCTAGCTCGGGTTAGTGTTCGACCCCTGCTTGAGAGCA
TGCAGAAGCAGCAGTCCTTTGTGGAAAATGCCAGTCATGAGTTACGGACTCCACTTGCAGTTTTGCAAAATCGCTTAGAG
ACCCTTTTCCGTAAGCCAGAAGCTACCATTATGGATGTGAGCGAAAGTATTGCATCGAGTTTGGAAGAAGTCCGAAATAT
GCGTTTTTTGACGACAAACTTGCTGAACTTAGCTCGGAGAGATGATGGGATTAAGCCGGAGCTTGCAGAAGTTCCAACTA
GTTTTTTCAATACGACTTTCACAAACTATGAGATGATTGCTTCGGAAAATGATCGTGTCTTCCGTTTTGAAAATCGTATC
CATCGTCCGATTGTCACAGACCAGCTTCTCTTGAAGCAGTTGATGACTATCCTATTTGATAATGCTGTCAAGTATACTGA
AGAGGATGGTGAAATTGATTTTCTTATCTCGGCGACCGATCGTAATCTGTATTTACTGGTTTCTGATAATGGAGTCGGTA
TTTCGACAGAAGATAAAAAGAAAATTTTTGATCGTTTTTATCGAGTGGACAAGGCTAGAACTCGTCAAAAAGGTGGTTTC
GGTTTAGGATTATCTCTGGCCAAGCAAATTGTAGATGCGCTTAAAGGAACCATTACTGTTAAAGATAATAAACCCAAGGG
AACAATCTTTGAAGTGAAGATTGCTATCCACACACCATCGAAAAAGAAAAAATAA
ATGTTCAGTAAACTAAAAAAAACATGGTATGCGGATGATTTTAGTTATTTTATCCGCAACTTTGGTGTCTTCACTCTGAT
TTTCTCTACCATGACTCTGATTATTTTACAGGTCATGCACTCGAGTCTCTATACTTCAGTGGATGATAAGCTCCACGTAC
TAAGTGAAAATCCTCAAGCAGTTATTCAACTGGCAGTGAATAGGGCAACAGAAGAGATTAAAGATTTAGAAAATGCTAGG
GCGGACGCTAGTAAAGTAGAAATAAAACCTAATGTCAGTTCCAATACGGAAGTCATTCTCTTTGATAAGGACTTTACTCA
ACTTCTTTCTGGAAATCGATTTTTGGGCTTGGATAAGATTAGGTTAGAGAAAAAAGAACTAGGCCATATCTACCAGATTC
AGGTTTTTAATAGCTATGGGCAGGAAGAAATCTATCGCATGATTTTGATGGAAACCAATATCAGTTCGGTTTCAACCAAT
ATCAAGTATGCTGCTGTCTTGATAAATACCAGTCAGTTGGAGCAGGCCAGTCAAAAGCATGAGCAATTGATTGTCGTTGT
GATGGTAAGTTTCTGGATTTTGTCTTTGCTTGCAAGTCTTTATCTAGCTCGGGTTAGTGTTCGACCCCTGCTTGAGAGCA
TGCAGAAGCAGCAGTCCTTTGTGGAAAATGCCAGTCATGAGTTACGGACTCCACTTGCAGTTTTGCAAAATCGCTTAGAG
ACCCTTTTCCGTAAGCCAGAAGCTACCATTATGGATGTGAGCGAAAGTATTGCATCGAGTTTGGAAGAAGTCCGAAATAT
GCGTTTTTTGACGACAAACTTGCTGAACTTAGCTCGGAGAGATGATGGGATTAAGCCGGAGCTTGCAGAAGTTCCAACTA
GTTTTTTCAATACGACTTTCACAAACTATGAGATGATTGCTTCGGAAAATGATCGTGTCTTCCGTTTTGAAAATCGTATC
CATCGTCCGATTGTCACAGACCAGCTTCTCTTGAAGCAGTTGATGACTATCCTATTTGATAATGCTGTCAAGTATACTGA
AGAGGATGGTGAAATTGATTTTCTTATCTCGGCGACCGATCGTAATCTGTATTTACTGGTTTCTGATAATGGAGTCGGTA
TTTCGACAGAAGATAAAAAGAAAATTTTTGATCGTTTTTATCGAGTGGACAAGGCTAGAACTCGTCAAAAAGGTGGTTTC
GGTTTAGGATTATCTCTGGCCAAGCAAATTGTAGATGCGCTTAAAGGAACCATTACTGTTAAAGATAATAAACCCAAGGG
AACAATCTTTGAAGTGAAGATTGCTATCCACACACCATCGAAAAAGAAAAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ciaH | Streptococcus pneumoniae Rx1 |
97.523 |
100 |
0.975 |
| ciaH | Streptococcus pneumoniae D39 |
97.523 |
100 |
0.975 |
| ciaH | Streptococcus pneumoniae R6 |
97.523 |
100 |
0.975 |
| ciaH | Streptococcus pneumoniae TIGR4 |
97.523 |
100 |
0.975 |
| ciaH | Streptococcus mutans UA159 |
56.322 |
97.973 |
0.552 |