Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SALIVB_RS04215 Genome accession   NC_015760
Coordinates   958166..959581 (+) Length   471 a.a.
NCBI ID   WP_013990466.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 953166..964581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS04190 (SALIVB_0856) - 953616..954188 (-) 573 WP_013990461.1 ECF transporter S component -
  SALIVB_RS04195 (SALIVB_0857) coaC 954217..954762 (-) 546 WP_013990462.1 phosphopantothenoylcysteine decarboxylase -
  SALIVB_RS04200 (SALIVB_0858) - 954755..955438 (-) 684 WP_013990463.1 phosphopantothenate--cysteine ligase -
  SALIVB_RS04205 (SALIVB_0859) - 955633..957303 (+) 1671 WP_013990464.1 formate--tetrahydrofolate ligase -
  SALIVB_RS04210 (SALIVB_0860) ciaR 957502..958176 (+) 675 WP_013990465.1 response regulator transcription factor Regulator
  SALIVB_RS04215 (SALIVB_0861) ciaH 958166..959581 (+) 1416 WP_013990466.1 sensor histidine kinase Regulator
  SALIVB_RS04220 (SALIVB_0862) rpsT 959659..959895 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  SALIVB_RS04225 (SALIVB_0863) coaA 959965..960885 (-) 921 WP_013990467.1 type I pantothenate kinase -
  SALIVB_RS04230 (SALIVB_0864) - 960998..961588 (+) 591 WP_013990468.1 class I SAM-dependent methyltransferase -
  SALIVB_RS04235 (SALIVB_0865) - 961585..962862 (+) 1278 WP_013990469.1 pyrimidine-nucleoside phosphorylase -
  SALIVB_RS04240 (SALIVB_0866) deoC 962896..963558 (+) 663 WP_013990470.1 deoxyribose-phosphate aldolase -
  SALIVB_RS04245 (SALIVB_0867) - 963545..963943 (+) 399 WP_013990471.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53464.22 Da        Isoelectric Point: 8.7661

>NTDB_id=41823 SALIVB_RS04215 WP_013990466.1 958166..959581(+) (ciaH) [Streptococcus salivarius CCHSS3]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGATTETSDSSDSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=41823 SALIVB_RS04215 WP_013990466.1 958166..959581(+) (ciaH) [Streptococcus salivarius CCHSS3]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACGACCATTTACCAGGCTTATGATACTAAAGGGGCGACAACTGAAACATCTGACTCGAGTGA
CTCTAAGAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCAGTTGCGGCAAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTTAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AATATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAGAAAGT
AGACAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGGTTAGAAGTTCTTTTCCGCAAGCCTGAGAGTACTATTTTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATTACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.522

97.665

0.552
  ciaH Streptococcus pneumoniae Rx1

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae D39

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae R6

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae TIGR4

50.431

98.514

0.497

Multiple sequence alignment