Detailed information NTG0417159

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3T08_RS12795
• Genome accession: NZ_CP047815
• Coordinates: 2608550..2609437 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain UP_1484
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2603550..2614437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3T08_RS12765 (E3T08_12765)	-	2603569..2603661 (+)	93	WP_010956583.1	hypothetical protein	-
E3T08_RS12770 (E3T08_12770)	-	2603769..2604266 (-)	498	WP_001065268.1	glutathione peroxidase	-
E3T08_RS12775 (E3T08_12775)	-	2604276..2604536 (-)	261	WP_001791974.1	hypothetical protein	-
E3T08_RS12780 (E3T08_12780)	-	2604918..2605031 (-)	114	Protein_2482	hypothetical protein	-
E3T08_RS12785 (E3T08_12785)	-	2605690..2607690 (-)	2001	WP_000776740.1	ABC transporter permease	-
E3T08_RS12790 (E3T08_12790)	-	2607687..2608442 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3T08_RS12795 (E3T08_12795)	braS	2608550..2609437 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3T08_RS12800 (E3T08_12800)	braR	2609448..2610113 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3T08_RS12805 (E3T08_12805)	-	2610139..2610339 (-)	201	WP_000604727.1	hypothetical protein	-
E3T08_RS12810 (E3T08_12810)	-	2610537..2611961 (+)	1425	WP_000953748.1	alkaline phosphatase	-
E3T08_RS13510	-	2612021..2612122 (-)	102	WP_000731972.1	SE2200 family small protein	-
E3T08_RS12820 (E3T08_12820)	-	2612244..2612699 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3T08_RS12825 (E3T08_12825)	-	2612944..2613705 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=417159 E3T08_RS12795 WP_000143417.1 2608550..2609437(-) (braS) [Staphylococcus aureus strain UP_1484]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=417159 E3T08_RS12795 WP_000143417.1 2608550..2609437(-) (braS) [Staphylococcus aureus strain UP_1484]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99