Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   H7786_RS08770 Genome accession   NZ_CP060649
Coordinates   1784375..1784971 (-) Length   198 a.a.
NCBI ID   WP_002991359.1    Uniprot ID   Q1JJH3
Organism   Streptococcus pyogenes strain TSPY270     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1779375..1789971
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7786_RS08735 (H7786_08785) - 1779435..1779740 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  H7786_RS08740 (H7786_08790) ruvX 1779752..1780171 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  H7786_RS08745 (H7786_08795) - 1780168..1780437 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  H7786_RS08750 (H7786_08800) spx 1780551..1780949 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  H7786_RS08755 (H7786_08805) recA 1781241..1782377 (-) 1137 WP_023612576.1 recombinase RecA Machinery gene
  H7786_RS08760 (H7786_08810) cinA 1782465..1783736 (-) 1272 WP_030126182.1 competence/damage-inducible protein A Machinery gene
  H7786_RS08765 (H7786_08815) - 1783805..1784365 (-) 561 WP_011018314.1 DNA-3-methyladenine glycosylase I -
  H7786_RS08770 (H7786_08820) ruvA 1784375..1784971 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA Machinery gene
  H7786_RS08775 (H7786_08825) - 1784973..1786194 (-) 1222 Protein_1687 MDR family MFS transporter -
  H7786_RS08780 (H7786_08830) hexB 1786205..1788187 (-) 1983 WP_030126181.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21841.15 Da        Isoelectric Point: 6.2537

>NTDB_id=416591 H7786_RS08770 WP_002991359.1 1784375..1784971(-) (ruvA) [Streptococcus pyogenes strain TSPY270]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=416591 H7786_RS08770 WP_002991359.1 1784375..1784971(-) (ruvA) [Streptococcus pyogenes strain TSPY270]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Helix-hairpin-helix domain (HHH_5)

(71-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JJH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae R6

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae D39

67.513

99.495

0.672
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424