Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   H7792_RS08295 Genome accession   NZ_CP060643
Coordinates   1708705..1709301 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain TSPY416     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1703705..1714301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS08260 (H7792_08230) - 1703766..1704071 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  H7792_RS08265 (H7792_08235) ruvX 1704083..1704502 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  H7792_RS08270 (H7792_08240) - 1704499..1704768 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  H7792_RS08275 (H7792_08245) spx 1704881..1705279 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  H7792_RS08280 (H7792_08250) recA 1705570..1706706 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  H7792_RS08285 (H7792_08255) cinA 1706795..1708066 (-) 1272 WP_136284910.1 competence/damage-inducible protein A Machinery gene
  H7792_RS08290 (H7792_08260) - 1708135..1708695 (-) 561 WP_136098684.1 DNA-3-methyladenine glycosylase I -
  H7792_RS08295 (H7792_08265) ruvA 1708705..1709301 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  H7792_RS08300 (H7792_08270) - 1709303..1710523 (-) 1221 WP_032461237.1 MDR family MFS transporter -
  H7792_RS08305 (H7792_08275) hexB 1710534..1712516 (-) 1983 WP_228650343.1 DNA mismatch repair endonuclease MutL Machinery gene
  H7792_RS08310 (H7792_08280) - 1712611..1713762 (-) 1152 WP_014635780.1 tyrosine-type recombinase/integrase -
  H7792_RS08315 (H7792_08285) - 1714011..1714154 (+) 144 WP_011185066.1 putative holin-like toxin -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=416020 H7792_RS08295 WP_002992186.1 1708705..1709301(-) (ruvA) [Streptococcus pyogenes strain TSPY416]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=416020 H7792_RS08295 WP_002992186.1 1708705..1709301(-) (ruvA) [Streptococcus pyogenes strain TSPY416]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419

Multiple sequence alignment