Detailed information NTG0416021

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3T03_RS09295
• Genome accession: NZ_CP047783
• Coordinates: 1921713..1922756 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UP_1313
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1916713..1927756

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3T03_RS09265 (E3T03_09265)	-	1917134..1918390 (-)	1257	WP_078065149.1	aminopeptidase	-
E3T03_RS09270 (E3T03_09270)	-	1918393..1918593 (-)	201	WP_000180460.1	DUF1128 family protein	-
E3T03_RS09275 (E3T03_09275)	-	1918740..1919204 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
E3T03_RS09280 (E3T03_09280)	-	1919211..1919486 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
E3T03_RS09285 (E3T03_09285)	-	1919764..1920981 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
E3T03_RS09290 (E3T03_09290)	vraR	1921094..1921723 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
E3T03_RS09295 (E3T03_09295)	vraS	1921713..1922756 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
E3T03_RS09300 (E3T03_09300)	liaF	1922753..1923454 (-)	702	WP_031919966.1	cell wall-active antibiotics response protein LiaF	-
E3T03_RS09305 (E3T03_09305)	-	1923469..1923855 (-)	387	WP_001110179.1	hypothetical protein	-
E3T03_RS09310 (E3T03_09310)	map	1924072..1924830 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
E3T03_RS09315 (E3T03_09315)	-	1925359..1926345 (+)	987	WP_000999708.1	FUSC family protein	-
E3T03_RS09320 (E3T03_09320)	-	1926778..1927191 (-)	414	WP_025174552.1	hypothetical protein	-
E3T03_RS09325 (E3T03_09325)	-	1927220..1927330 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=416021 E3T03_RS09295 WP_001017131.1 1921713..1922756(-) (vraS) [Staphylococcus aureus strain UP_1313]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=416021 E3T03_RS09295 WP_001017131.1 1921713..1922756(-) (vraS) [Staphylococcus aureus strain UP_1313]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1