Detailed information NTG0414827

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: GTW26_RS26785
• Genome accession: NZ_CP047643
• Coordinates: 5668089..5669426 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa CI27
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5663089..5674426

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GTW26_RS26760 (GTW26_26695)	pgeF	5663232..5663960 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
GTW26_RS26765 (GTW26_26700)	rluD	5663957..5664919 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
GTW26_RS26770 (GTW26_26705)	-	5665065..5666090 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
GTW26_RS26775 (GTW26_26710)	-	5666247..5666492 (+)	246	WP_003102591.1	PP0621 family protein	-
GTW26_RS26780 (GTW26_26715)	pilS	5666482..5668074 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
GTW26_RS26785 (GTW26_26720)	pilR	5668089..5669426 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
GTW26_RS26790 (GTW26_26725)	thiO	5669472..5670566 (-)	1095	WP_003141551.1	glycine oxidase ThiO	-
GTW26_RS26795 (GTW26_26730)	-	5670706..5671206 (+)	501	WP_016254062.1	GspH/FimT family pseudopilin	-
GTW26_RS26800 (GTW26_26735)	-	5671329..5671817 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
GTW26_RS26805 (GTW26_26740)	pilV	5671827..5672351 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
GTW26_RS26810 (GTW26_26745)	-	5672360..5673175 (+)	816	WP_016254061.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
GTW26_RS26815 (GTW26_26750)	-	5673172..5673777 (+)	606	WP_003116263.1	pilus assembly protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=414827 GTW26_RS26785 WP_003094694.1 5668089..5669426(+) (pilR) [Pseudomonas aeruginosa CI27]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=414827 GTW26_RS26785 WP_003094694.1 5668089..5669426(+) (pilR) [Pseudomonas aeruginosa CI27]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTACGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384