Detailed information NTG0414695

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: GU334_RS07765
• Genome accession: NZ_CP047628
• Coordinates: 1601095..1603347 (-)
• Length: 750 a.a.
• NCBI ID: WP_245325536.1
• Uniprot ID: -
• Organism: Lactococcus raffinolactis strain Lr_19_14
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1596095..1608347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GU334_RS07735 (GU334_07700)	atpA	1596352..1597857 (-)	1506	WP_061773979.1	F0F1 ATP synthase subunit alpha	-
GU334_RS07740 (GU334_07705)	-	1597998..1598525 (-)	528	WP_061773978.1	F0F1 ATP synthase subunit delta	-
GU334_RS07745 (GU334_07710)	atpF	1598528..1599037 (-)	510	WP_061773977.1	F0F1 ATP synthase subunit B	-
GU334_RS07750 (GU334_07715)	atpB	1599050..1599760 (-)	711	WP_167841439.1	F0F1 ATP synthase subunit A	-
GU334_RS07755 (GU334_07720)	-	1599866..1600066 (-)	201	WP_003140734.1	F0F1 ATP synthase subunit C	-
GU334_RS07760 (GU334_07725)	-	1600222..1601016 (-)	795	WP_096039369.1	alpha/beta hydrolase family protein	-
GU334_RS07765 (GU334_07730)	comEC	1601095..1603347 (-)	2253	WP_245325536.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GU334_RS07770 (GU334_07735)	-	1603313..1603966 (-)	654	WP_244165981.1	helix-hairpin-helix domain-containing protein	-
GU334_RS07775 (GU334_07740)	-	1604024..1605244 (-)	1221	WP_157738471.1	ABC transporter permease	-
GU334_RS07780 (GU334_07745)	-	1605237..1606130 (-)	894	WP_061773972.1	ABC transporter ATP-binding protein	-
GU334_RS07785 (GU334_07750)	-	1606305..1606739 (-)	435	WP_061773971.1	hypothetical protein	-
GU334_RS07790 (GU334_07755)	-	1606795..1606989 (-)	195	WP_061773970.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 750 a.a.
• Molecular weight: 85551.69 Da
• Isoelectric Point: 10.1525

>NTDB_id=414695 GU334_RS07765 WP_245325536.1 1601095..1603347(-) (comEC) [Lactococcus raffinolactis strain Lr_19_14]
MKNLKKALRWINLPSIFIAYFCVLIYYTVFCFSYLLLGYLIISLLILIWQNGIRTCLKLSMILIGFATICLALQDREAKD
FAREMTVTRISPILDTIQVDGDQVSFRGKSGKQTYQVYYRVTTEQEQRYFKQLAQPVVLSISGQLEKASQQRNFNGFDYQ
HHLKSQNIYRVLTIEQVTGVTRKQTLTLALLRRKAILFSEQHFPRPMSAYMTGLLFGHLGKDFEDMSSIYTSLGIMHLFA
LSGMQVSFFIDFLRKGMLRLGFRRDVVDWFQIPFSVFYAGLTGFSISVNRSLVQKILANFGIKALDNFSLTLLLLFITAP
KFLLTTGGTLSLLFAFVISIFGDRFENLPKYRKLLAESLTLSLCVLPLLILYFHTFQPVSIILTFVFSFLFDILFLPGLS
VIFLLAMVTGFTLTQVNLIFQWLEDLIKLTDSWWHYPLVLGKPTALVFLAMLVVTGLLIDHWRNRKVSARLAIILMGLFF
ITKNPPTPSITMVDVGQGDSIFLQDKFNRRNILIDTGGRIELGKKKKWQERKIAAPAEKTLIPYLKSRGVGQIDTLVLTH
THEDHMGDLLAVIDQIKVKNIIVSQGSLNNAQFVKLLKQTRAKVQVAKVGQRLKIFDSYLEVLYPLTPGDGKNNDSIVLY
GKLYGTKFLLTGDLEETGERELLTRYPNLSVDVLKVGHHGSKTSSSESFIEAIRPKVGLISCGLDNRYGHPNMETLTTFQ
KYEVQTFRTDYHGAIKFKKNSKFWHISTVK

Nucleotide

• Length: 2253 bp

>NTDB_id=414695 GU334_RS07765 WP_245325536.1 1601095..1603347(-) (comEC) [Lactococcus raffinolactis strain Lr_19_14]
TTGAAAAACTTAAAGAAAGCATTACGGTGGATTAATCTACCATCGATTTTCATCGCCTATTTTTGTGTGCTGATCTACTA
TACCGTCTTTTGTTTCTCCTATTTACTTTTAGGTTATCTCATCATTTCTTTGCTAATCTTGATCTGGCAAAATGGCATCA
GAACTTGTTTAAAGCTCAGCATGATCTTAATTGGGTTTGCAACCATTTGTCTAGCGCTACAAGATCGTGAAGCTAAAGAT
TTTGCGCGTGAGATGACAGTGACACGGATCAGCCCCATACTGGATACGATTCAGGTGGATGGTGACCAGGTCTCTTTTCG
TGGGAAATCGGGCAAACAAACCTATCAAGTCTATTATAGGGTCACGACGGAACAAGAGCAGCGCTACTTTAAGCAATTAG
CACAACCAGTCGTCCTATCCATTTCAGGTCAACTAGAAAAAGCGAGTCAACAAAGAAATTTCAATGGCTTTGATTATCAA
CACCATCTCAAGTCACAAAATATCTATCGAGTTTTGACGATTGAACAGGTGACAGGGGTGACAAGAAAACAAACCTTAAC
CTTAGCGCTCTTACGACGAAAAGCTATTTTGTTTAGTGAGCAACACTTTCCGCGACCTATGTCAGCCTACATGACCGGTT
TACTTTTTGGGCATCTCGGTAAAGATTTTGAAGATATGAGCAGTATCTATACCAGCTTAGGCATCATGCACCTCTTTGCG
CTATCAGGCATGCAAGTGTCATTTTTTATCGACTTTTTAAGAAAGGGTATGCTCAGACTAGGGTTCAGGAGAGATGTTGT
CGATTGGTTTCAAATCCCTTTTTCTGTTTTTTATGCTGGTCTTACAGGATTTTCCATATCTGTCAACAGATCCTTGGTCC
AGAAAATCCTAGCTAATTTTGGAATTAAGGCGCTTGACAATTTCAGTCTCACGTTGTTGCTTCTATTTATCACGGCGCCA
AAATTCCTTTTAACCACAGGCGGCACCTTGTCTTTACTTTTTGCCTTCGTCATTTCAATCTTTGGTGATCGCTTTGAGAA
CCTCCCAAAATATCGTAAACTACTAGCAGAAAGTTTAACCCTTTCTCTATGCGTTTTACCGCTCCTCATCCTTTATTTTC
ACACCTTCCAACCAGTGTCGATCATCTTGACCTTTGTCTTCAGCTTTCTTTTTGATATTCTCTTCCTACCAGGTCTATCC
GTCATTTTCTTGCTAGCAATGGTAACAGGCTTCACGCTAACACAAGTCAATCTCATTTTTCAGTGGCTTGAAGACCTTAT
CAAATTGACAGATAGCTGGTGGCATTATCCGTTAGTACTTGGTAAACCAACAGCCTTGGTCTTTCTGGCAATGCTAGTTG
TGACAGGTTTATTAATTGACCACTGGCGAAATCGAAAAGTTAGTGCTAGGCTGGCAATCATCTTGATGGGCTTATTCTTC
ATAACTAAAAATCCACCGACTCCTTCGATAACCATGGTGGATGTTGGCCAGGGGGATAGTATTTTCTTACAAGATAAGTT
TAATCGACGCAATATTTTAATCGATACAGGTGGCAGGATTGAACTAGGTAAGAAGAAAAAGTGGCAGGAGCGTAAAATTG
CAGCACCAGCTGAAAAGACTTTAATTCCTTATTTGAAAAGTCGGGGTGTGGGTCAGATTGATACTTTGGTTCTAACCCAT
ACTCACGAGGACCATATGGGTGACCTACTCGCTGTCATCGACCAAATTAAGGTCAAAAATATCATCGTGAGTCAAGGCAG
TCTCAATAATGCCCAATTTGTCAAACTCTTAAAGCAAACCCGAGCTAAGGTTCAAGTGGCCAAGGTCGGTCAACGACTAA
AGATTTTTGACAGCTATTTGGAAGTTCTGTATCCATTGACCCCAGGAGATGGTAAAAATAATGACTCGATCGTCTTGTAT
GGTAAGCTCTATGGGACAAAATTTTTGTTAACAGGTGATTTGGAGGAGACAGGCGAGCGAGAGTTGTTGACACGTTATCC
CAATCTCTCAGTTGATGTTTTAAAAGTAGGGCATCATGGCTCAAAAACGTCATCTTCTGAGTCTTTTATTGAAGCGATTC
GACCAAAAGTCGGATTGATTTCTTGTGGTTTGGATAATCGGTACGGTCATCCAAATATGGAAACTCTCACAACCTTCCAG
AAATATGAGGTTCAAACTTTTCGAACAGATTATCATGGTGCTATAAAATTTAAGAAAAACAGTAAATTTTGGCACATCTC
GACAGTAAAGTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (214-463)

• Domain of unknown function (DUF4131) (DUF4131) (34-178)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-703)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	52.227	98.8	0.516
comEC/celB	Streptococcus mitis NCTC 12261	46.95	100	0.472
comEC/celB	Streptococcus mitis SK321	46.367	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	44.782	100	0.452
comEC/celB	Streptococcus pneumoniae Rx1	43.989	100	0.444
comEC/celB	Streptococcus pneumoniae D39	43.989	100	0.444
comEC/celB	Streptococcus pneumoniae R6	43.989	100	0.444