Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GU336_RS02840 Genome accession   NZ_CP047616
Coordinates   547162..547854 (+) Length   230 a.a.
NCBI ID   WP_003139754.1    Uniprot ID   A0A1K2HC77
Organism   Lactococcus raffinolactis strain Lr_19_5     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 542162..552854
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GU336_RS02815 (GU336_02815) - 542681..543613 (+) 933 WP_138492253.1 manganese-dependent inorganic pyrophosphatase -
  GU336_RS02820 (GU336_02820) rpsN 543710..543979 (+) 270 WP_096039979.1 30S ribosomal protein S14 -
  GU336_RS02825 (GU336_02825) - 544055..544837 (-) 783 WP_138492254.1 ABC transporter ATP-binding protein -
  GU336_RS02830 (GU336_02830) - 544927..545466 (+) 540 WP_096039981.1 YceD family protein -
  GU336_RS02835 (GU336_02835) gndA 545669..547090 (+) 1422 WP_167838425.1 NADP-dependent phosphogluconate dehydrogenase -
  GU336_RS02840 (GU336_02840) covR 547162..547854 (+) 693 WP_003139754.1 response regulator transcription factor Regulator
  GU336_RS02845 (GU336_02845) - 548084..549574 (+) 1491 WP_167838426.1 HAMP domain-containing histidine kinase -
  GU336_RS02850 (GU336_02850) - 549766..551004 (+) 1239 WP_167838427.1 ammonium transporter -
  GU336_RS02855 (GU336_02855) - 551060..551401 (+) 342 WP_167838428.1 P-II family nitrogen regulator -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26902.68 Da        Isoelectric Point: 5.5396

>NTDB_id=414637 GU336_RS02840 WP_003139754.1 547162..547854(+) (covR) [Lactococcus raffinolactis strain Lr_19_5]
MGKKILIIEDEKQLARFVSLELEHEGYSVETRHDGRSGLEAAMTQEWDMILLDLMLPELDGFEVARRLRNEKQTPITIMT
ARDSTMDKVAGLDIGADDYITKPFAIEELLARLRANFRRQDREVQKRKKTDGTTFRDLIINKKNRQVQRGEEIIDLTKRE
YDLLTTLMKNVNDVVTREQLVQNVWGYEEGTETNVVDVYIRYLRNKLDQKGKDSYIQTVRGLGYMLRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=414637 GU336_RS02840 WP_003139754.1 547162..547854(+) (covR) [Lactococcus raffinolactis strain Lr_19_5]
ATGGGAAAAAAAATTCTAATCATCGAAGATGAAAAACAACTCGCGCGTTTTGTATCACTTGAGCTCGAACACGAAGGATA
TAGCGTTGAAACACGTCATGATGGCCGTAGCGGTCTCGAAGCAGCTATGACACAAGAATGGGACATGATCCTTTTGGATT
TGATGTTGCCTGAATTGGACGGTTTCGAAGTAGCGCGTCGCTTGCGCAATGAAAAACAAACACCAATTACAATCATGACA
GCTCGTGATAGTACAATGGACAAAGTCGCTGGTCTTGATATCGGTGCAGATGACTATATCACAAAACCATTTGCGATTGA
AGAGTTGCTAGCGCGTCTTCGTGCTAACTTCCGTCGTCAAGATCGTGAAGTTCAAAAACGTAAGAAAACTGATGGCACAA
CTTTCCGTGACTTGATCATTAACAAGAAAAACCGTCAAGTCCAACGTGGCGAAGAAATTATTGATTTGACAAAACGCGAA
TACGATTTGTTGACAACTTTGATGAAAAACGTTAACGATGTTGTGACACGTGAACAACTTGTTCAAAATGTTTGGGGCTA
TGAAGAAGGGACTGAAACAAACGTTGTTGATGTCTACATTCGTTACCTCCGTAATAAACTCGATCAAAAAGGTAAAGACT
CATATATCCAAACTGTTCGTGGCTTGGGTTACATGTTACGCGAGAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1K2HC77

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

74.89

98.696

0.739
  covR Streptococcus salivarius strain HSISS4

66.228

99.13

0.657
  micA Streptococcus pneumoniae Cp1015

42.437

100

0.439
  vicR Streptococcus mutans UA159

41.88

100

0.426

Multiple sequence alignment