Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GU337_RS01970 Genome accession   NZ_CP047614
Coordinates   389090..389782 (+) Length   230 a.a.
NCBI ID   WP_061773771.1    Uniprot ID   A0A2A5SI44
Organism   Lactococcus raffinolactis strain Lr_19_7     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 384090..394782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GU337_RS01945 (GU337_01945) - 384609..385541 (+) 933 WP_167839717.1 manganese-dependent inorganic pyrophosphatase -
  GU337_RS01950 (GU337_01950) rpsN 385638..385907 (+) 270 WP_096039979.1 30S ribosomal protein S14 -
  GU337_RS01955 (GU337_01955) - 385983..386765 (-) 783 WP_138492254.1 ABC transporter ATP-binding protein -
  GU337_RS01960 (GU337_01960) - 386855..387394 (+) 540 WP_096039981.1 YceD family protein -
  GU337_RS01965 (GU337_01965) gndA 387597..389018 (+) 1422 WP_096039982.1 NADP-dependent phosphogluconate dehydrogenase -
  GU337_RS01970 (GU337_01970) covR 389090..389782 (+) 693 WP_061773771.1 response regulator transcription factor Regulator
  GU337_RS01975 (GU337_01975) - 390012..391502 (+) 1491 WP_061773772.1 HAMP domain-containing histidine kinase -
  GU337_RS01980 (GU337_01980) - 391694..392932 (+) 1239 WP_167839718.1 ammonium transporter -
  GU337_RS01985 (GU337_01985) - 392988..393329 (+) 342 WP_061773774.1 P-II family nitrogen regulator -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26862.65 Da        Isoelectric Point: 5.2972

>NTDB_id=414584 GU337_RS01970 WP_061773771.1 389090..389782(+) (covR) [Lactococcus raffinolactis strain Lr_19_7]
MGKKILIIEDEKQLARFVSLELEHEGYSVETRPDGRSGLEAAMTQEWDMILLDLMLPELDGFEVARRLRNEKQTPITIMT
ARDSTMDKVAGLDIGADDYITKPFAIEELLARLRANFRRQDREVQKRKKTDGTTFRDLIINKKNRQVQRGEEIIDLTKRE
YDLLTTLMKNVNDVVTREQLVQNVWGYEEGTETNVVDVYIRYLRNKLDQKGKDSYIQTVRGLGYMLRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=414584 GU337_RS01970 WP_061773771.1 389090..389782(+) (covR) [Lactococcus raffinolactis strain Lr_19_7]
ATGGGAAAAAAAATTCTAATCATCGAAGATGAAAAACAACTCGCGCGTTTTGTATCACTTGAGCTCGAACACGAAGGATA
TAGCGTTGAAACACGTCCTGATGGCCGTAGCGGTCTCGAAGCAGCTATGACACAAGAATGGGACATGATCCTTTTGGATT
TGATGTTGCCTGAATTGGACGGTTTCGAAGTAGCGCGTCGCTTGCGCAATGAAAAACAAACACCAATTACAATCATGACA
GCTCGTGATAGTACAATGGACAAAGTCGCTGGTCTTGATATCGGTGCAGATGACTATATCACAAAACCATTTGCGATTGA
AGAGTTGCTAGCGCGTCTTCGTGCTAACTTCCGTCGTCAAGATCGTGAAGTCCAAAAACGTAAGAAAACTGATGGCACAA
CTTTCCGTGACTTGATCATTAACAAGAAAAACCGTCAAGTCCAACGTGGCGAAGAAATTATTGATTTGACAAAACGCGAA
TACGATTTGTTGACAACTTTGATGAAAAATGTTAACGATGTTGTGACACGTGAACAACTTGTTCAAAATGTTTGGGGCTA
TGAAGAAGGGACTGAAACAAATGTTGTTGATGTCTACATTCGTTACCTCCGTAATAAACTCGATCAAAAAGGTAAAGACT
CATATATCCAAACTGTTCGTGGCTTGGGTTACATGTTACGCGAGAATAATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-226)

Response regulator receiver domain (Response_reg)

(5-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A5SI44

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

74.89

98.696

0.739
  covR Streptococcus salivarius strain HSISS4

66.228

99.13

0.657
  micA Streptococcus pneumoniae Cp1015

42.437

100

0.439
  vicR Streptococcus mutans UA159

41.88

100

0.426

Multiple sequence alignment