Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   UM146_RS19630 Genome accession   NC_017632
Coordinates   3941156..3942148 (+) Length   330 a.a.
NCBI ID   WP_000224467.1    Uniprot ID   B7MGH3
Organism   Escherichia coli UM146     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 3936156..3947148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UM146_RS19605 (UM146_18930) rbsD 3936280..3936699 (+) 420 WP_001350412.1 D-ribose pyranase -
  UM146_RS19610 (UM146_18935) rbsA 3936707..3938212 (+) 1506 WP_000387779.1 ribose ABC transporter ATP-binding protein RbsA -
  UM146_RS19615 (UM146_18940) rbsC 3938217..3939182 (+) 966 WP_000211858.1 ribose ABC transporter permease -
  UM146_RS19620 (UM146_18945) rbsB 3939207..3940097 (+) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  UM146_RS19625 (UM146_18950) rbsK 3940223..3941152 (+) 930 WP_001361088.1 ribokinase -
  UM146_RS19630 (UM146_18955) cytR 3941156..3942148 (+) 993 WP_000224467.1 ribose operon transcriptional repressor RbsR Regulator
  UM146_RS19635 (UM146_18960) mdtD 3942114..3943541 (-) 1428 WP_001280824.1 multidrug transporter subunit MdtD -
  UM146_RS19640 (UM146_18965) yieP 3943564..3944256 (-) 693 WP_001131161.1 FadR/GntR family transcriptional regulator -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36581.88 Da        Isoelectric Point: 5.2141

>NTDB_id=41415 UM146_RS19630 WP_000224467.1 3941156..3942148(+) (cytR) [Escherichia coli UM146]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPALQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=41415 UM146_RS19630 WP_000224467.1 3941156..3942148(+) (cytR) [Escherichia coli UM146]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACAGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTTGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGTAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAGCCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACCGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATTGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCCATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCTGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACAACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGGCCCTACAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGTGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(3-48)

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7MGH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364

Multiple sequence alignment