Detailed information NTG0041368

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: HMPREF0833_RS01005
• Genome accession: NC_015678
• Coordinates: 193143..194093 (+)
• Length: 316 a.a.
• NCBI ID: WP_013903305.1
• Uniprot ID: I1ZL05
• Organism: Streptococcus parasanguinis ATCC 15912
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 188143..199093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0833_RS00985 (HMPREF0833_10188)	-	188833..189540 (+)	708	WP_003017792.1	glucosamine-6-phosphate deaminase	-
HMPREF0833_RS00990 (HMPREF0833_10189)	-	189729..191078 (+)	1350	WP_013903302.1	DUF1958 domain-containing protein	-
HMPREF0833_RS00995 (HMPREF0833_10190)	-	191146..192318 (+)	1173	WP_013903303.1	MFS transporter	-
HMPREF0833_RS01000 (HMPREF0833_10191)	-	192487..193068 (+)	582	WP_013903304.1	hypothetical protein	-
HMPREF0833_RS01005 (HMPREF0833_10192)	coiA	193143..194093 (+)	951	WP_013903305.1	competence protein CoiA	Machinery gene
HMPREF0833_RS01010 (HMPREF0833_10193)	pepF	194166..195968 (+)	1803	WP_013903306.1	oligoendopeptidase F	Regulator
HMPREF0833_RS01015 (HMPREF0833_10194)	-	195970..196689 (+)	720	WP_013903307.1	O-methyltransferase	-
HMPREF0833_RS01020 (HMPREF0833_10195)	prsA	196762..197706 (+)	945	WP_013903308.1	peptidylprolyl isomerase PrsA	-
HMPREF0833_RS01025 (HMPREF0833_10196)	-	197960..198445 (+)	486	WP_041818133.1	LURP-one-related/scramblase family protein	-

Sequence

Protein

• Length: 316 a.a.
• Molecular weight: 37762.24 Da
• Isoelectric Point: 6.9943

>NTDB_id=41368 HMPREF0833_RS01005 WP_013903305.1 193143..194093(+) (coiA) [Streptococcus parasanguinis ATCC 15912]
MFIAMDNNQQRWNCIKEVPPTTAGPFYCLACHSQVRLKNGSVLRAHFAHVELQHCPYHHEAESFEHLELKASLYDWASKE
SKTEVESYLADFQQIADLLVVDKNLALEVQCSSLSLERLKERSDAYRSHGYQVYWLLGKKLWLKERLTKLQAGFLYFSQN
RGFHLWELDLAKKELRLQYLIHEDLRGRLHYQTEIFPFGQRSLLEVLRTPYLSQSMQQMAVELDRTFLTYIQQQLFYRHP
KWMRFQEELYLQGHHLLELGLDFFYPLCRPILSQNLLQIEEDVEGYYQQFMAYYQSQGIQPVQILYPPRFYAQQKS

Nucleotide

• Length: 951 bp

>NTDB_id=41368 HMPREF0833_RS01005 WP_013903305.1 193143..194093(+) (coiA) [Streptococcus parasanguinis ATCC 15912]
ATGTTTATTGCCATGGATAACAATCAACAGAGGTGGAACTGTATCAAGGAGGTCCCACCTACAACAGCTGGTCCTTTCTA
TTGCTTGGCTTGTCACAGTCAAGTGCGTCTAAAAAATGGCTCGGTTCTACGGGCTCATTTTGCTCATGTAGAATTACAGC
ATTGTCCCTATCATCACGAAGCTGAGAGTTTTGAACATCTGGAATTGAAAGCCAGTCTTTATGATTGGGCCTCTAAGGAG
TCTAAAACAGAGGTAGAAAGTTATTTAGCAGACTTTCAACAAATTGCCGATCTTTTGGTAGTAGACAAGAACTTAGCTTT
GGAAGTGCAGTGTAGCTCCTTATCTTTAGAACGCTTGAAGGAGAGAAGCGATGCTTATCGATCCCACGGTTACCAGGTCT
ATTGGTTACTTGGTAAAAAGTTGTGGCTCAAGGAAAGACTAACAAAACTGCAGGCTGGCTTTCTTTATTTTAGTCAGAAT
CGAGGTTTTCATCTTTGGGAATTGGATCTGGCAAAGAAAGAGCTACGTTTACAATACCTCATTCATGAGGATTTACGAGG
GCGATTGCATTATCAAACAGAAATTTTCCCTTTTGGTCAAAGGTCTTTACTGGAAGTCTTACGGACCCCTTATCTTTCGC
AATCCATGCAACAAATGGCAGTCGAGCTCGATCGGACATTTTTAACGTATATACAGCAGCAACTCTTTTATCGTCACCCA
AAGTGGATGAGGTTTCAGGAAGAACTCTATTTGCAGGGACACCATCTACTGGAACTAGGCTTGGATTTCTTTTATCCTCT
TTGTCGTCCGATCCTTTCACAGAACTTACTCCAAATTGAAGAGGATGTAGAAGGTTACTACCAGCAATTTATGGCCTATT
ATCAGTCGCAAGGGATCCAACCTGTTCAGATCCTCTATCCTCCACGTTTTTATGCTCAACAGAAAAGCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (25-266)

3D structure

• AlphaFold DB: I1ZL05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	51.757	99.051	0.513
coiA	Streptococcus pneumoniae Rx1	50.799	99.051	0.503
coiA	Streptococcus pneumoniae D39	50.799	99.051	0.503
coiA	Streptococcus pneumoniae R6	50.799	99.051	0.503
coiA	Streptococcus pneumoniae TIGR4	50.799	99.051	0.503
coiA	Lactococcus lactis subsp. cremoris KW2	42.857	100	0.437