Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   H6X75_RS10360 Genome accession   NZ_CP060156
Coordinates   2037394..2037876 (-) Length   160 a.a.
NCBI ID   WP_155457965.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700608     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2032394..2042876
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H6X75_RS10330 (H6X75_10320) - 2032704..2033579 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  H6X75_RS10335 (H6X75_10325) pstC 2033697..2034560 (+) 864 WP_000595180.1 phosphate ABC transporter permease subunit PstC -
  H6X75_RS10340 (H6X75_10330) pstA 2034553..2035368 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  H6X75_RS10345 (H6X75_10335) pstB 2035370..2036122 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  H6X75_RS10350 (H6X75_10340) phoU 2036137..2036787 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  H6X75_RS10355 (H6X75_10345) - 2036849..2037271 (+) 423 Protein_2013 transposase -
  H6X75_RS10360 (H6X75_10350) comR 2037394..2037876 (-) 483 WP_155457965.1 helix-turn-helix transcriptional regulator Regulator
  H6X75_RS10365 (H6X75_10355) - 2038046..2039062 (+) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  H6X75_RS10370 (H6X75_10360) galU 2039084..2039983 (+) 900 WP_000202235.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  H6X75_RS10375 (H6X75_10365) - 2040055..2040732 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  H6X75_RS10380 (H6X75_10370) - 2040716..2041255 (-) 540 WP_000834318.1 5-formyltetrahydrofolate cyclo-ligase -
  H6X75_RS10385 (H6X75_10375) - 2041267..2042397 (-) 1131 WP_000885067.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19203.11 Da        Isoelectric Point: 4.8839

>NTDB_id=413573 H6X75_RS10360 WP_155457965.1 2037394..2037876(-) (comR) [Streptococcus pneumoniae strain PZ900700608]
MLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLEVEDYKLMPS
YIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 483 bp        

>NTDB_id=413573 H6X75_RS10360 WP_155457965.1 2037394..2037876(-) (comR) [Streptococcus pneumoniae strain PZ900700608]
ATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTT
GGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATG
GAGAATCCAGACCAACACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGT
TATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATCGC
CCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCC
CAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGG
TGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(86-133)

Helix-turn-helix (HTH_3)

(22-73)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

75

0.419
  comR Streptococcus pyogenes MGAS315

54.167

75

0.406
  comR Streptococcus mutans UA159

53.333

75

0.4
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

53.636

68.75

0.369