Detailed information NTG0413558

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H6X75_RS09720
• Genome accession: NZ_CP060156
• Coordinates: 1931443..1932264 (-)
• Length: 273 a.a.
• NCBI ID: WP_000904827.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700608
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1926443..1937264

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H6X75_RS09695 (H6X75_09690)	rsmA	1926668..1927540 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
H6X75_RS09700 (H6X75_09695)	-	1927791..1928084 (-)	294	WP_000333255.1	hypothetical protein	-
H6X75_RS09705 (H6X75_09700)	-	1928077..1928718 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
H6X75_RS09710 (H6X75_09705)	-	1928720..1930750 (-)	2031	WP_000825244.1	bacteriocin-associated integral membrane family protein	-
H6X75_RS09715 (H6X75_09710)	-	1930827..1931123 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
H6X75_RS09720 (H6X75_09715)	comR	1931443..1932264 (-)	822	WP_000904827.1	XRE family transcriptional regulator	Regulator
H6X75_RS09725 (H6X75_09720)	rnmV	1932336..1932896 (-)	561	WP_000660019.1	ribonuclease M5	-
H6X75_RS09730 (H6X75_09725)	-	1932896..1933669 (-)	774	WP_000575601.1	TatD family hydrolase	-
H6X75_RS09735 (H6X75_09730)	-	1933974..1934867 (-)	894	WP_000226485.1	DUF1542 domain-containing protein	-
H6X75_RS09740 (H6X75_09735)	rpmH	1935151..1935285 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
H6X75_RS09745 (H6X75_09740)	-	1935693..1936646 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-

Sequence

Protein

• Length: 273 a.a.
• Molecular weight: 32180.61 Da
• Isoelectric Point: 6.1110

>NTDB_id=413558 H6X75_RS09720 WP_000904827.1 1931443..1932264(-) (comR) [Streptococcus pneumoniae strain PZ900700608]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLLIRLFFYQMLIRKDLAKFINQIEKLML
FLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAES
FYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 822 bp

>NTDB_id=413558 H6X75_RS09720 WP_000904827.1 1931443..1932264(-) (comR) [Streptococcus pneumoniae strain PZ900700608]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTATGATAAGAAAGAAGCGTGTTTGGATACTTCTAGAACTAGAAGGCC
TGAATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGT
TGATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTC
TTTCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTG
TCTTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATT
ATCAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCA
TTTTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGA
GGATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (94-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	34.564	100	0.377
comR	Streptococcus mutans UA159	34.354	100	0.37
comR	Streptococcus suis P1/7	34.364	100	0.366
comR	Streptococcus suis 05ZYH33	34.364	100	0.366
comR	Streptococcus pyogenes MGAS315	33.333	100	0.366