Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   H6X75_RS00110 Genome accession   NZ_CP060156
Coordinates   22170..22406 (+) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700608     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 17170..27406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H6X75_RS00100 (H6X75_00100) - 20226..21072 (+) 847 Protein_14 IS630 family transposase -
  H6X75_RS00105 (H6X75_00105) - 21107..21904 (-) 798 Protein_15 transposase -
  H6X75_RS00110 (H6X75_00110) comW 22170..22406 (+) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  H6X75_RS00115 (H6X75_00115) - 22637..23923 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  H6X75_RS00120 (H6X75_00120) - 24187..25335 (-) 1149 WP_000876727.1 site-specific integrase -
  H6X75_RS00125 (H6X75_00125) - 25506..26306 (-) 801 WP_000539947.1 HIRAN domain-containing protein -
  H6X75_RS00130 (H6X75_00130) - 26433..27188 (-) 756 WP_000069476.1 XRE family transcriptional regulator -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=413469 H6X75_RS00110 WP_000939544.1 22170..22406(+) (comW) [Streptococcus pneumoniae strain PZ900700608]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=413469 H6X75_RS00110 WP_000939544.1 22170..22406(+) (comW) [Streptococcus pneumoniae strain PZ900700608]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974
  comW Streptococcus pneumoniae D39

97.436

100

0.974
  comW Streptococcus pneumoniae R6

97.436

100

0.974
  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974
  comW Streptococcus mitis SK321

78.205

100

0.782
  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769